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• W1510773602 abstract "ABS TRACT Ob jec ti ve: To in ves ti ga te the ad di ti ve ef fect of et ha nol and ni co ti ne on rat li ver oxi da ti ve sta tus fol lo wing eit her alo ne or com bi ned sub-chro nic ad mi nis tra ti on. Ma te ri al and Met hods: Forty-eight fe ma le Spra gu e Dew ley rats we re gro u ped ran domly in to one of the pro to cols, which con sis ted of tre at ment for 10 days with et ha nol 2 g/kg/day (et ha nol gro up, n= 12), ni co ti ne 0.15 mg/kg/day (ni co ti ne gro up, n= 12), both drugs (et ha nol plus ni co ti ne gro up, n= 12) or sa li ne so lu ti on (con trol gro up, n= 10) for 10 days. Fol lo wing 10 days of ad mi nis tra ti on of the sethe abovementioned agents, ma lon di al dehy de con cen tra ti on, re du ced glu tat hi o ne con cen tra ti on and glu tat hi o ne pe ro xi da se ac ti vity we re as ses sed in the li ver. Re sults: The et ha nol plus ni co ti ne gro up had sig ni fi cantly hig her ma lon di al dehy de and lo wer glu tat hi o ne con cen tra ti ons than eit her the et ha nol and ni co ti ne and the con trol gro ups (both, p 0.05). No sig ni fi cant dif fe ren ce was ob ser ved in glu tat hi o ne pe ro xi da se ac ti vity of et ha nol, ni co ti ne or et ha nol plus ni co ti ne gro ups (all p> 0.05). Conc lu si ons: Co-ad mi nis tra ti on of et ha nol and ni co ti ne re sults with sig ni fi cant in cre a se in li pid pe ro xi da ti on and sig ni fi cant dec re a se in glu tathionele vels com pa red to their separate ad mi nis tra ti on." @default.
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• W1510773602 date "2009-01-01" @default.
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• W1510773602 title "Ethanol and Nicotine Interaction on Liver Oxidative Status: An Experimental Study" @default.
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