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- W1511041692 abstract "Discussion Culture conditions were appropriate for EP viability, but not sufficient to maintain EP phenotype (GAG loss, EP thinning). Will investigate the capacity of high osmotic pressure (similar to native nucleus pulposus environment) to impede proteoglycan loss in EP explant culture. Introduction Intervertebral discs (IVDs) consist of a firm, flexible outer layer (annulus fibrosus) surrounding a gelatinous, compressible core (nucleus pulposus). Endplates (EPs) are cartilaginous layers that lie between the IVD and the vertebral body (Fig. 1). As nucleus pulposus is avascular, its nutrient and oxygen supply relies on diffusion from the vertebral body blood vessels through the EPs [1]." @default.
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- W1511041692 date "2009-01-01" @default.
- W1511041692 modified "2023-09-22" @default.
- W1511041692 title "Culturing disc endplates" @default.
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