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- W1511155704 abstract "Researchers have been attempting for decades to elucidate the molecular mechanisms at play within the cells that cause the development of cancer. There is now growing evidence that cancers may form from cancer stem cells. Somehow, a group of cells evolves that are immortal and can produce progenitor cells that can grow; however, the research community doesn’t know how these cells lose control. Recent studies have suggested the existence of a special small subpopulation of cancer cells that act as tumor-initiating cells or cancer stem cells. Cancer stem cells are implicated to maintain the self-renewal and unlimited growth capabilities of the cancer while only comprising a small fraction of the tumor. For this reason, cancer stem cells may be responsible for the tumor progression, drug/treatment resistance development, and metastasis. Other studies have demonstrated that microRNAs (miRNAs) have a great deal to do with what genes are expressed/not expressed through their gene silencing capabilities. Interestingly, microRNAs might provide some new insight into the intricacies of cancer. These small RNA molecules could hold great potential therapeutically in the battle against cancer. In this chapter, we discuss the functions of microRNAs and cancer stem cells and explore the link between these two topics. We also present methods to use in current and future research to study these topics and expound upon various molecular therapy options that could have implications in correcting cancer stem cell dysregulation and battling oncogenesis." @default.
- W1511155704 created "2016-06-24" @default.
- W1511155704 creator A5013509540 @default.
- W1511155704 creator A5046132413 @default.
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- W1511155704 date "2011-03-22" @default.
- W1511155704 modified "2023-10-16" @default.
- W1511155704 title "MicroRNAs: Small but Critical Regulators of Cancer Stem Cells" @default.
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- W1511155704 cites W1596473475 @default.
- W1511155704 cites W1816419917 @default.
- W1511155704 cites W1835280798 @default.
- W1511155704 cites W1964631913 @default.
- W1511155704 cites W1971645224 @default.
- W1511155704 cites W1972989638 @default.
- W1511155704 cites W1977506341 @default.
- W1511155704 cites W1977677497 @default.
- W1511155704 cites W1977836335 @default.
- W1511155704 cites W1979421565 @default.
- W1511155704 cites W1983876698 @default.
- W1511155704 cites W1990361620 @default.
- W1511155704 cites W1999636129 @default.
- W1511155704 cites W1999746960 @default.
- W1511155704 cites W2009229545 @default.
- W1511155704 cites W2009886857 @default.
- W1511155704 cites W2012582486 @default.
- W1511155704 cites W2012962381 @default.
- W1511155704 cites W2013842709 @default.
- W1511155704 cites W2014064723 @default.
- W1511155704 cites W2014509855 @default.
- W1511155704 cites W2014929974 @default.
- W1511155704 cites W2020124057 @default.
- W1511155704 cites W2020833650 @default.
- W1511155704 cites W2023427658 @default.
- W1511155704 cites W2029758324 @default.
- W1511155704 cites W2032582943 @default.
- W1511155704 cites W2034527747 @default.
- W1511155704 cites W2036656484 @default.
- W1511155704 cites W2040489812 @default.
- W1511155704 cites W2040851084 @default.
- W1511155704 cites W2041988668 @default.
- W1511155704 cites W2045786960 @default.
- W1511155704 cites W2047262284 @default.
- W1511155704 cites W2050079849 @default.
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- W1511155704 cites W2057846741 @default.
- W1511155704 cites W2061165346 @default.
- W1511155704 cites W2066195397 @default.
- W1511155704 cites W2069104846 @default.
- W1511155704 cites W2070647652 @default.
- W1511155704 cites W2077364468 @default.
- W1511155704 cites W2077841029 @default.
- W1511155704 cites W2082298210 @default.
- W1511155704 cites W2085592081 @default.
- W1511155704 cites W2086227770 @default.
- W1511155704 cites W2096330673 @default.
- W1511155704 cites W2103211592 @default.
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- W1511155704 cites W2130376575 @default.
- W1511155704 cites W2131596261 @default.
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- W1511155704 cites W2138343959 @default.
- W1511155704 cites W2140152239 @default.
- W1511155704 cites W2144038313 @default.
- W1511155704 cites W2146027678 @default.
- W1511155704 cites W2146074268 @default.
- W1511155704 cites W2146997290 @default.
- W1511155704 cites W2149385948 @default.
- W1511155704 cites W2149784145 @default.
- W1511155704 cites W2153478835 @default.
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- W1511155704 cites W2167837485 @default.
- W1511155704 cites W2168230240 @default.
- W1511155704 cites W2168750261 @default.
- W1511155704 cites W2169145911 @default.
- W1511155704 cites W2170086508 @default.
- W1511155704 cites W2336183884 @default.
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- W1511155704 doi "https://doi.org/10.5772/15099" @default.
- W1511155704 hasPublicationYear "2011" @default.
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