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- W1511389619 abstract "In case of diseased intracranial arterial walls focal or segmental dilatations may develop, which are referred to as cerebral aneurysms. If a rupture sets in, consequences are often devastating. In this work two patient-specific cerebral aneurysms are investigated by means of CFD (Computational Fluid Dynamics) simulations. In both cases a rupture occurred during the medical examination without any manipulation. Hence, both configurations can be used in an attempt to characterize specifically the location of rupture. Unsteady hemodynamic simulations are carried out on high-quality block-structured grids. Besides velocity and pressure distribution, temporally averaged wall shear stresses (AWSS) as well as the oscillatory shear index (OSI) are analyzed. Neither elevated velocity nor pressure values are found within the area of interest. However, an oscillating flow motion is identified that may influence the endothelial cell layer. Increased AWSS and OSI appear mainly at the neck of the aneurysms and distal to the bifurcations, respectively, disqualifying them as driving factors regarding a rupture in the present configurations." @default.
- W1511389619 created "2016-06-24" @default.
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- W1511389619 date "2012-01-01" @default.
- W1511389619 modified "2023-10-05" @default.
- W1511389619 title "Characterization Of The Ruptured Site In Intracranial Aneurysms Based On CFD Computations" @default.
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