FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1511507145> ?p ?o ?g. }

• W1511507145 endingPage "745" @default.
• W1511507145 startingPage "727" @default.
• W1511507145 abstract "Listeners with normal audiometric thresholds can still have suprathreshold deficits, for example, in the ability to discriminate sounds in complex acoustic scenes. One likely source of these deficits is cochlear neuropathy, a loss of auditory nerve (AN) fibers without hair cell damage, which can occur due to both aging and moderate acoustic overexposure. Since neuropathy can affect up to 50 % of AN fibers, its impact on suprathreshold hearing is likely profound, but progress is hindered by lack of a robust non-invasive test of neuropathy in humans. Reduction of suprathreshold auditory brainstem responses (ABRs) can be used to quantify neuropathy in inbred mice. However, ABR amplitudes are highly variable in humans, and thus more challenging to use. Since noise-induced neuropathy is selective for AN fibers with high thresholds, and because phase locking to temporal envelopes is particularly strong in these fibers, the envelope following response (EFR) might be a more robust measure. We compared EFRs to sinusoidally amplitude-modulated tones and ABRs to tone-pips in mice following a neuropathic noise exposure. EFR amplitude, EFR phase-locking value, and ABR amplitude were all reduced in noise-exposed mice. However, the changes in EFRs were more robust: the variance was smaller, thus inter-group differences were clearer. Optimum detection of neuropathy was achieved with high modulation frequencies and moderate levels. Analysis of group delays was used to confirm that the AN population was dominating the responses at these high modulation frequencies. Application of these principles in clinical testing can improve the differential diagnosis of sensorineural hearing loss." @default.
• W1511507145 created "2016-06-24" @default.
• W1511507145 creator A5024427965 @default.
• W1511507145 creator A5035701879 @default.
• W1511507145 creator A5074057821 @default.
• W1511507145 date "2015-09-01" @default.
• W1511507145 modified "2023-10-15" @default.
• W1511507145 title "Towards a Diagnosis of Cochlear Neuropathy with Envelope Following Responses" @default.
• W1511507145 cites W144356152 @default.
• W1511507145 cites W1543088917 @default.
• W1511507145 cites W1948588766 @default.
• W1511507145 cites W1966970502 @default.
• W1511507145 cites W1967315405 @default.
• W1511507145 cites W1972168487 @default.
• W1511507145 cites W1973780031 @default.
• W1511507145 cites W1975935202 @default.
• W1511507145 cites W1983735466 @default.
• W1511507145 cites W1986899373 @default.
• W1511507145 cites W1987022414 @default.
• W1511507145 cites W1988778615 @default.
• W1511507145 cites W1991963103 @default.
• W1511507145 cites W1992890284 @default.
• W1511507145 cites W1993272861 @default.
• W1511507145 cites W1993801920 @default.
• W1511507145 cites W2000718865 @default.
• W1511507145 cites W2003588229 @default.
• W1511507145 cites W2004847756 @default.
• W1511507145 cites W2008182962 @default.
• W1511507145 cites W2009984517 @default.
• W1511507145 cites W2011415025 @default.
• W1511507145 cites W2011889205 @default.
• W1511507145 cites W2013496968 @default.
• W1511507145 cites W2016785002 @default.
• W1511507145 cites W2021821090 @default.
• W1511507145 cites W2030980369 @default.
• W1511507145 cites W2038917130 @default.
• W1511507145 cites W2045032466 @default.
• W1511507145 cites W2051642304 @default.
• W1511507145 cites W2053068031 @default.
• W1511507145 cites W2057725339 @default.
• W1511507145 cites W2058781453 @default.
• W1511507145 cites W2060308684 @default.
• W1511507145 cites W2062180190 @default.
• W1511507145 cites W2063128058 @default.
• W1511507145 cites W2063969154 @default.
• W1511507145 cites W2067363387 @default.
• W1511507145 cites W2067422268 @default.
• W1511507145 cites W2069111106 @default.
• W1511507145 cites W2070390087 @default.
• W1511507145 cites W2072517993 @default.
• W1511507145 cites W2074378742 @default.
• W1511507145 cites W2076281129 @default.
• W1511507145 cites W2088565339 @default.
• W1511507145 cites W2090345596 @default.
• W1511507145 cites W2092526100 @default.
• W1511507145 cites W2092663121 @default.
• W1511507145 cites W2097498366 @default.
• W1511507145 cites W2113556125 @default.
• W1511507145 cites W2122977468 @default.
• W1511507145 cites W2124770269 @default.
• W1511507145 cites W2125415737 @default.
• W1511507145 cites W2126219184 @default.
• W1511507145 cites W2130714199 @default.
• W1511507145 cites W2137045294 @default.
• W1511507145 cites W2137106144 @default.
• W1511507145 cites W2140150081 @default.
• W1511507145 cites W2141570304 @default.
• W1511507145 cites W2160483038 @default.
• W1511507145 cites W2161803347 @default.
• W1511507145 cites W2161851299 @default.
• W1511507145 cites W2165991867 @default.
• W1511507145 cites W2171993659 @default.
• W1511507145 cites W2314835883 @default.
• W1511507145 cites W2397128548 @default.
• W1511507145 cites W2414643769 @default.
• W1511507145 cites W2417727188 @default.
• W1511507145 doi "https://doi.org/10.1007/s10162-015-0539-3" @default.
• W1511507145 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4636593" @default.
• W1511507145 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26323349" @default.
• W1511507145 hasPublicationYear "2015" @default.
• W1511507145 type Work @default.
• W1511507145 sameAs 1511507145 @default.
• W1511507145 citedByCount "160" @default.
• W1511507145 countsByYear W15115071452016 @default.
• W1511507145 countsByYear W15115071452017 @default.
• W1511507145 countsByYear W15115071452018 @default.
• W1511507145 countsByYear W15115071452019 @default.
• W1511507145 countsByYear W15115071452020 @default.
• W1511507145 countsByYear W15115071452021 @default.
• W1511507145 countsByYear W15115071452022 @default.
• W1511507145 countsByYear W15115071452023 @default.
• W1511507145 crossrefType "journal-article" @default.
• W1511507145 hasAuthorship W1511507145A5024427965 @default.
• W1511507145 hasAuthorship W1511507145A5035701879 @default.
• W1511507145 hasAuthorship W1511507145A5074057821 @default.
• W1511507145 hasBestOaLocation W15115071452 @default.
• W1511507145 hasConcept C115961682 @default.
• W1511507145 hasConcept C11930861 @default.

• next