FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1511547982> ?p ?o ?g. }

• W1511547982 endingPage "7449" @default.
• W1511547982 startingPage "7441" @default.
• W1511547982 abstract "The transcriptional activator retinoic acid (RA) has been shown to influence the early patterning of the vertebrate eye. Models for the establishment of the retinofugal projection postulate gradients of cell-surface markers across the retinal surface that are expressed by ganglion cells and mediate the correct connection of fibers within central target fields. Spatial asymmetries of RA and RA-producing enzymes, as have been found in the eyes of mice and zebrafish, could induce the required asymmetry in gene expression. Here we exploited the large size of the retina of the embryonic chick to analyze the spatial and temporal characteristics of the RA system by HPLC in combination with a reporter cell assay. As in other embryonic vertebrates, the chick retina was found to contain different RA-generating enzymes segregated along the dorsoventral axis. The major RA isomer in both dorsal and ventral retina was all-trans RA, and no 9-cis RA could be detected. This excludes a difference in production of these two isomers as an explanation for the expression of different RA-generating enzymes. At developmental stages embryonic days (E) 4 and 5, the ventral retina contained higher all-trans RA levels than the dorsal retina. After E8, however, the difference disappeared, and in embryos at E9 and older the RA concentration was slightly higher in dorsal than ventral retina." @default.
• W1511547982 created "2016-06-24" @default.
• W1511547982 creator A5013725557 @default.
• W1511547982 creator A5037680649 @default.
• W1511547982 creator A5076029463 @default.
• W1511547982 date "1997-10-01" @default.
• W1511547982 modified "2023-09-29" @default.
• W1511547982 title "Retinoic Acid Synthesis in the Developing Chick Retina" @default.
• W1511547982 cites W117813152 @default.
• W1511547982 cites W1234126864 @default.
• W1511547982 cites W1545922126 @default.
• W1511547982 cites W1570165358 @default.
• W1511547982 cites W1574038640 @default.
• W1511547982 cites W1618929865 @default.
• W1511547982 cites W1850838207 @default.
• W1511547982 cites W1880270297 @default.
• W1511547982 cites W1977455576 @default.
• W1511547982 cites W1983134628 @default.
• W1511547982 cites W1983678271 @default.
• W1511547982 cites W1984755886 @default.
• W1511547982 cites W1995754186 @default.
• W1511547982 cites W1997693108 @default.
• W1511547982 cites W2000532942 @default.
• W1511547982 cites W2002652075 @default.
• W1511547982 cites W2012892360 @default.
• W1511547982 cites W2016567075 @default.
• W1511547982 cites W2018753490 @default.
• W1511547982 cites W2027876857 @default.
• W1511547982 cites W2028884889 @default.
• W1511547982 cites W2033076791 @default.
• W1511547982 cites W2035275306 @default.
• W1511547982 cites W2041710680 @default.
• W1511547982 cites W2045232172 @default.
• W1511547982 cites W2046473105 @default.
• W1511547982 cites W2050357018 @default.
• W1511547982 cites W2057908565 @default.
• W1511547982 cites W2065288649 @default.
• W1511547982 cites W2068191133 @default.
• W1511547982 cites W2071230039 @default.
• W1511547982 cites W2074658209 @default.
• W1511547982 cites W2083761568 @default.
• W1511547982 cites W2086345206 @default.
• W1511547982 cites W2092047281 @default.
• W1511547982 cites W2105165411 @default.
• W1511547982 cites W2118323778 @default.
• W1511547982 cites W2125161058 @default.
• W1511547982 cites W2138434278 @default.
• W1511547982 cites W2140034535 @default.
• W1511547982 cites W2144853475 @default.
• W1511547982 cites W2151164511 @default.
• W1511547982 cites W2187327173 @default.
• W1511547982 cites W2500975048 @default.
• W1511547982 cites W4251899320 @default.
• W1511547982 doi "https://doi.org/10.1523/jneurosci.17-19-07441.1997" @default.
• W1511547982 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6573435" @default.
• W1511547982 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9295390" @default.
• W1511547982 hasPublicationYear "1997" @default.
• W1511547982 type Work @default.
• W1511547982 sameAs 1511547982 @default.
• W1511547982 citedByCount "51" @default.
• W1511547982 countsByYear W15115479822013 @default.
• W1511547982 countsByYear W15115479822014 @default.
• W1511547982 countsByYear W15115479822016 @default.
• W1511547982 countsByYear W15115479822019 @default.
• W1511547982 countsByYear W15115479822020 @default.
• W1511547982 countsByYear W15115479822021 @default.
• W1511547982 crossrefType "journal-article" @default.
• W1511547982 hasAuthorship W1511547982A5013725557 @default.
• W1511547982 hasAuthorship W1511547982A5037680649 @default.
• W1511547982 hasAuthorship W1511547982A5076029463 @default.
• W1511547982 hasBestOaLocation W15115479821 @default.
• W1511547982 hasConcept C104317684 @default.
• W1511547982 hasConcept C105702510 @default.
• W1511547982 hasConcept C145103041 @default.
• W1511547982 hasConcept C169760540 @default.
• W1511547982 hasConcept C2776878037 @default.
• W1511547982 hasConcept C2777093970 @default.
• W1511547982 hasConcept C2781121885 @default.
• W1511547982 hasConcept C54355233 @default.
• W1511547982 hasConcept C86803240 @default.
• W1511547982 hasConcept C95444343 @default.
• W1511547982 hasConceptScore W1511547982C104317684 @default.
• W1511547982 hasConceptScore W1511547982C105702510 @default.
• W1511547982 hasConceptScore W1511547982C145103041 @default.
• W1511547982 hasConceptScore W1511547982C169760540 @default.
• W1511547982 hasConceptScore W1511547982C2776878037 @default.
• W1511547982 hasConceptScore W1511547982C2777093970 @default.
• W1511547982 hasConceptScore W1511547982C2781121885 @default.
• W1511547982 hasConceptScore W1511547982C54355233 @default.
• W1511547982 hasConceptScore W1511547982C86803240 @default.
• W1511547982 hasConceptScore W1511547982C95444343 @default.
• W1511547982 hasIssue "19" @default.
• W1511547982 hasLocation W15115479821 @default.
• W1511547982 hasLocation W15115479822 @default.
• W1511547982 hasLocation W15115479823 @default.
• W1511547982 hasLocation W15115479824 @default.
• W1511547982 hasOpenAccess W1511547982 @default.
• W1511547982 hasPrimaryLocation W15115479821 @default.

• next