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- W1511565595 abstract "To review the current data for the use of Botulinum toxin type A (BoNT-A) in trigeminal neuralgia (TN) and to describe the preferred injection technique of BoNT-A in TN. To propose a new treatment paradigm for TN incorporating the use BoNT-A.MEDLINE and Google Scholar databases.The current data on BoNT-A for TN were reviewed and analyzed for outcomes.Seven studies examining the use of BoNT-A were identified: Two randomized double-blind, placebo-controlled studies and five prospective case series. All studies found BoNT-A to be an effective treatment in the majority of patients; and the results of the two randomized double-blind placebo-controlled study showed significant benefit over placebo. The majority of studies used an intradermal or subcutaneous injection technique. The most common side effect was transient facial paresis.BoNT-A offers a safe, effective, local treatment for TN that is nonablative in nature. BoNT-A should be considered in patients who have failed, become refractory to, or are unable to tolerate first-line pharmacologic treatments.N/A." @default.
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- W1511565595 date "2013-08-05" @default.
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- W1511565595 title "A new treatment paradigm for trigeminal neuralgia using botulinum toxin type a" @default.
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- W1511565595 doi "https://doi.org/10.1002/lary.24286" @default.
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