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- W1512029204 abstract "In the last years, an increasing number of results are being obtained in the field of using membrane systems to model different biological phenomena. This has been done both at the microscopical level as well as at the macroscopic level. The purpose of the present work is to adequately model the activation of the Notch pathway (using membrane computing). Notch activation is described in detail in [9], which is clearly summarised in [8], including all relevant references and diagrams (the important Notch activation diagram is in [9]). Of course, the first task that is required to be done is the specification of the membrane system model that is going to be used. This will be done within the software framework P-Lingua 2.0 , in order to allow an easy route towards a software simulation of the designed model. Biologists usually use static model of pathways in an aid to understanding, so it will be really beneficial for them to get access to an effective representation of the activation of Notch in a dynamic computer model. Ideally (and in the long term) the model should be able to shed light on some important questions (listed at the end of the present document), specially if computer simulations can be run." @default.
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- W1512029204 date "2009-01-01" @default.
- W1512029204 modified "2023-10-02" @default.
- W1512029204 title "A First Attempt to Model Notch Signalling by Means of P Systems" @default.
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