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- W1512431337 abstract "Abstract In this chapter, various proposals for optional subdivision of the existing T, N and M categories, i.e., “telescopic” ramification, are presented. Telescoping accommodates the collection of additional data without altering the definitions of the existing TNM categories. The concept of telescoping permits an orderly expansion of TNM elements to allow for testing of subcategories for prognosis and treatment planning considerations. Telescoping accommodates “splitters” and “lumpers”, permits data from expansions to collapse into the standard categories and promotes testing of new hypotheses uniformly in different centres. The editors recognize that staging has to be simple enough for universal use in both highly developed and developing countries and sufficiently uncomplicated so that medical professionals are not discouraged from using the system. On the other hand, for specialized institutions and for investigational purposes a relatively simple staging system is not sufficient and runs the risk of not being used. For these specialized institutions the TNM system may be made more attractive by further subdivision of the existing categories (telescopic ramification) and by including additional descriptors. The proposals for subdivisions and additional designations in this section are presented for investigational use and are entirely optional . Some proposals relate to subclassifications of M1 and are of interest to oncologists. Justification for each proposal is given based on published data or clinical experience." @default.
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- W1512431337 date "2014-06-04" @default.
- W1512431337 modified "2023-10-16" @default.
- W1512431337 title "Optional Proposals for Testing New Telescopic Ramifications of TNM" @default.
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- W1512431337 doi "https://doi.org/10.1002/9780471420194.tnms05.pub3" @default.
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