FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1512434032> ?p ?o ?g. }

• W1512434032 endingPage "1048" @default.
• W1512434032 startingPage "1035" @default.
• W1512434032 abstract "To investigate the putative role of the photoreceptor connecting cilium in the delivery of opsin to forming discs and in the maintenance of membrane domains (Besharse, J. C., and K. H. Pfenninger (1980) J. Cell Biol. 87: 451-463), we have studied developing photoreceptors of neonatal rats during the period of initial disc formation using conventional freeze-fracture, immunocytochemistry, and lectin cytochemistry. Specific anti-opsin-binding sites were localized in the distal cilium, the developing outer segment plasma membrane, and at focal sites on the inner segment plasma membrane at all developmental stages examined, including the period prior to the onset of disc morphogenesis. The proximal ciliary shaft generally lacked anti-opsin-binding sites or exhibited them in extremely low density. The distribution of anti-opsin-binding sites corresponded in a general way to the distribution of large intramembranous particles (IMPs) in freeze-fracture replicas like those seen in the rod outer segment (ROS). The proximal zone corresponded in freeze-fracture images to a zone of consecutive horizontal rows of intramembrane particles (ciliary necklaces) and axoneme-membrane cross-linkers. Although protoplasmic face leaflet IMPs similar to those of the distal cilium and outer segment were less abundant in the inner segment and proximal cilium than in the distal cilium and ROS, they were detected in these zones at low frequency. Cytochemistry with concanavalin A and wheatgerm agglutinin revealed the presence of a well developed glycocalyx in the proximal zone. Although opsin binds both lectins, the results suggest heterogeneity among the glycoconjugates of the three membrane domains. Our data define distinct membrane domains of the developing photoreceptor cilium that have important implications for the mechanisms for delivering and sequestering opsin in the outer segment. They also establish that the mechanism of opsin delivery to the distal zone occurs well in advance of the period of disc morphogenesis." @default.
• W1512434032 created "2016-06-24" @default.
• W1512434032 creator A5054064862 @default.
• W1512434032 creator A5060566611 @default.
• W1512434032 creator A5077772918 @default.
• W1512434032 date "1985-04-01" @default.
• W1512434032 modified "2023-09-30" @default.
• W1512434032 title "Membrane assembly in retinal photoreceptors. III. Distinct membrane domains of the connecting cilium of developing rods" @default.
• W1512434032 cites W1583530091 @default.
• W1512434032 cites W1601047299 @default.
• W1512434032 cites W1963591622 @default.
• W1512434032 cites W1963732597 @default.
• W1512434032 cites W1967839393 @default.
• W1512434032 cites W1971071873 @default.
• W1512434032 cites W1984870448 @default.
• W1512434032 cites W1989452894 @default.
• W1512434032 cites W1995868380 @default.
• W1512434032 cites W2034912738 @default.
• W1512434032 cites W2043307069 @default.
• W1512434032 cites W2066162878 @default.
• W1512434032 cites W2066780072 @default.
• W1512434032 cites W2075228214 @default.
• W1512434032 cites W2086790354 @default.
• W1512434032 cites W2112275388 @default.
• W1512434032 cites W2127911529 @default.
• W1512434032 cites W2137100273 @default.
• W1512434032 cites W239541579 @default.
• W1512434032 cites W2488961548 @default.
• W1512434032 cites W94952055 @default.
• W1512434032 cites W9575570 @default.
• W1512434032 cites W98131189 @default.
• W1512434032 doi "https://doi.org/10.1523/jneurosci.05-04-01035.1985" @default.
• W1512434032 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6565013" @default.
• W1512434032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3156973" @default.
• W1512434032 hasPublicationYear "1985" @default.
• W1512434032 type Work @default.
• W1512434032 sameAs 1512434032 @default.
• W1512434032 citedByCount "94" @default.
• W1512434032 countsByYear W15124340322012 @default.
• W1512434032 countsByYear W15124340322013 @default.
• W1512434032 countsByYear W15124340322014 @default.
• W1512434032 countsByYear W15124340322015 @default.
• W1512434032 countsByYear W15124340322016 @default.
• W1512434032 countsByYear W15124340322017 @default.
• W1512434032 countsByYear W15124340322018 @default.
• W1512434032 countsByYear W15124340322019 @default.
• W1512434032 countsByYear W15124340322021 @default.
• W1512434032 countsByYear W15124340322022 @default.
• W1512434032 countsByYear W15124340322023 @default.
• W1512434032 crossrefType "journal-article" @default.
• W1512434032 hasAuthorship W1512434032A5054064862 @default.
• W1512434032 hasAuthorship W1512434032A5060566611 @default.
• W1512434032 hasAuthorship W1512434032A5077772918 @default.
• W1512434032 hasBestOaLocation W15124340321 @default.
• W1512434032 hasConcept C100094513 @default.
• W1512434032 hasConcept C104317684 @default.
• W1512434032 hasConcept C105702510 @default.
• W1512434032 hasConcept C115811362 @default.
• W1512434032 hasConcept C12554922 @default.
• W1512434032 hasConcept C134018914 @default.
• W1512434032 hasConcept C169760540 @default.
• W1512434032 hasConcept C202033177 @default.
• W1512434032 hasConcept C24870808 @default.
• W1512434032 hasConcept C2777093970 @default.
• W1512434032 hasConcept C2780827179 @default.
• W1512434032 hasConcept C30028475 @default.
• W1512434032 hasConcept C35866371 @default.
• W1512434032 hasConcept C55493867 @default.
• W1512434032 hasConcept C86803240 @default.
• W1512434032 hasConcept C87555872 @default.
• W1512434032 hasConcept C95444343 @default.
• W1512434032 hasConceptScore W1512434032C100094513 @default.
• W1512434032 hasConceptScore W1512434032C104317684 @default.
• W1512434032 hasConceptScore W1512434032C105702510 @default.
• W1512434032 hasConceptScore W1512434032C115811362 @default.
• W1512434032 hasConceptScore W1512434032C12554922 @default.
• W1512434032 hasConceptScore W1512434032C134018914 @default.
• W1512434032 hasConceptScore W1512434032C169760540 @default.
• W1512434032 hasConceptScore W1512434032C202033177 @default.
• W1512434032 hasConceptScore W1512434032C24870808 @default.
• W1512434032 hasConceptScore W1512434032C2777093970 @default.
• W1512434032 hasConceptScore W1512434032C2780827179 @default.
• W1512434032 hasConceptScore W1512434032C30028475 @default.
• W1512434032 hasConceptScore W1512434032C35866371 @default.
• W1512434032 hasConceptScore W1512434032C55493867 @default.
• W1512434032 hasConceptScore W1512434032C86803240 @default.
• W1512434032 hasConceptScore W1512434032C87555872 @default.
• W1512434032 hasConceptScore W1512434032C95444343 @default.
• W1512434032 hasIssue "4" @default.
• W1512434032 hasLocation W15124340321 @default.
• W1512434032 hasLocation W15124340322 @default.
• W1512434032 hasLocation W15124340323 @default.
• W1512434032 hasLocation W15124340324 @default.
• W1512434032 hasOpenAccess W1512434032 @default.
• W1512434032 hasPrimaryLocation W15124340321 @default.
• W1512434032 hasRelatedWork W166622744 @default.
• W1512434032 hasRelatedWork W2050928056 @default.
• W1512434032 hasRelatedWork W2068898416 @default.

• next