FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W151311370> ?p ?o ?g. }

• W151311370 endingPage "205" @default.
• W151311370 startingPage "187" @default.
• W151311370 abstract "The aim of this retrospective study was to characterize the risk factors of hepatic artery thrombosis (HAT) after orthotopic liver transplantation (OLT) in a consecutive series of 687 OLT, comparing the branch patch anastomosis (BPA) with the end-to-end anastomosis (EEA), in order to investigate, moreover, which technique may be statistically associated with a reduced incidence of HAT.Between 1986-1999 we performed 687 OLT in 601 patients, of which 592 were adult and 95 pediatric. Preservation of all donor livers was accomplished with the University of Wisconsin solution since OLT No. 112, at the beginning of 1990. A multivariate analysis was performed in order to find independent variables influencing HAT. We compared, between the two study groups EEA (n = 340) vs BPA (n = 347), HAT incidences with the following variables: adult OLT; pediatric OLT; pre '90 period; post '90 period; donor age; ABO incompatibility; graft type; cold ischemia time; warm ischemia time; double anastomoses; retransplantation; whole blood, fresh frozen plasma and platelet transfusions.HAT was identified in 17/687 OLT (2.47%). HAT incidence was 2.0% in adults (12/592) and 5.2% in children (5/95) (p = 0.059). In the EEA group, HAT was diagnosed in 12/340 cases (3.53%), whereas in the BPA group 5/347 patients experienced HAT (1.44%) (p = 0.078). The need of back table reconstruction occurred in 2/17 HAT cases (11.7%). Possible causative factors included rejection in 5 patients, whereas were unknown in 7 cases. A clear mechanical cause for HAT was identified in one patient, in whom a mechanical intraabdominal compression caused poor inflow. In two cases an intimal dissection was found, while poor inflow occurred in two cases. After a univariate analysis of 44 variables, compared between the two study groups (EEA vs BPA) in patients who developed HAT after OLT (n = 17), only intraoperative PT (p = 0.0525), postoperative SGOT (48 h) (p = 0.0006) and postoperative SGPT (48 h) (p = 0.0222) correlated significantly with the occurrence of HAT. After a multivariate analysis, the variables found to be independent in increasing HAT incidence were: pre '90 period (HAT incidence was 4.5 times more frequent in the pre '90 period: p = 0.0093), ABO incompatibility (HAT incidence was 7.8 times more frequent in incompatible cases: p = 0.0363) and a shorter warm ischemia time (p = 0.0112).HAT after OLT is more common in the pediatric population, where it occurs in 10% to 26% of the cases, considerably higher than the 1.6% to 10.5% rate seen in the adult patients. In our series the risk of thrombosis was 2.6 times greater in children than in adults. Moreover, after a multivariate analysis, it was observed that the EEA was associated with an increased risk of thrombosis (2.4 times greater than in the BPA group). In this retrospective study we described a large number of variables, that may influence the development of HAT after OLT, identifying a group of risk factors that correlated statistically with this complication. The results of our report stressed the importance of medical factors compared with surgical factors in the incidence of HAT.Even if the type of arterial reconstruction was not found to be an independent risk factor in reducing HAT incidence after OLT, our current preferred method of arterial anastomosis is the branch patch technique, using the hepatic-gastroduodenal bifurcation, with a HAT rate of 1.44%." @default.
• W151311370 created "2016-06-24" @default.
• W151311370 creator A5010084275 @default.
• W151311370 creator A5031860840 @default.
• W151311370 creator A5044377029 @default.
• W151311370 creator A5051611999 @default.
• W151311370 creator A5069364341 @default.
• W151311370 creator A5073339632 @default.
• W151311370 creator A5073894327 @default.
• W151311370 creator A5086249121 @default.
• W151311370 date "2001-09-13" @default.
• W151311370 modified "2023-10-18" @default.
• W151311370 title "[Assessment of risk factors in the incidence of hepatic artery thrombosis in a consecutive series of 687 liver transplantations]." @default.
• W151311370 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11552475" @default.
• W151311370 hasPublicationYear "2001" @default.
• W151311370 type Work @default.
• W151311370 sameAs 151311370 @default.
• W151311370 citedByCount "12" @default.
• W151311370 countsByYear W1513113702013 @default.
• W151311370 countsByYear W1513113702015 @default.
• W151311370 countsByYear W1513113702016 @default.
• W151311370 countsByYear W1513113702018 @default.
• W151311370 countsByYear W1513113702021 @default.
• W151311370 crossrefType "journal-article" @default.
• W151311370 hasAuthorship W151311370A5010084275 @default.
• W151311370 hasAuthorship W151311370A5031860840 @default.
• W151311370 hasAuthorship W151311370A5044377029 @default.
• W151311370 hasAuthorship W151311370A5051611999 @default.
• W151311370 hasAuthorship W151311370A5069364341 @default.
• W151311370 hasAuthorship W151311370A5073339632 @default.
• W151311370 hasAuthorship W151311370A5073894327 @default.
• W151311370 hasAuthorship W151311370A5086249121 @default.
• W151311370 hasConcept C120665830 @default.
• W151311370 hasConcept C121332964 @default.
• W151311370 hasConcept C126322002 @default.
• W151311370 hasConcept C141071460 @default.
• W151311370 hasConcept C176080213 @default.
• W151311370 hasConcept C2776820930 @default.
• W151311370 hasConcept C2778800853 @default.
• W151311370 hasConcept C2779609443 @default.
• W151311370 hasConcept C2780868729 @default.
• W151311370 hasConcept C2911091166 @default.
• W151311370 hasConcept C2991799789 @default.
• W151311370 hasConcept C61511704 @default.
• W151311370 hasConcept C71924100 @default.
• W151311370 hasConcept C8443397 @default.
• W151311370 hasConcept C90924648 @default.
• W151311370 hasConceptScore W151311370C120665830 @default.
• W151311370 hasConceptScore W151311370C121332964 @default.
• W151311370 hasConceptScore W151311370C126322002 @default.
• W151311370 hasConceptScore W151311370C141071460 @default.
• W151311370 hasConceptScore W151311370C176080213 @default.
• W151311370 hasConceptScore W151311370C2776820930 @default.
• W151311370 hasConceptScore W151311370C2778800853 @default.
• W151311370 hasConceptScore W151311370C2779609443 @default.
• W151311370 hasConceptScore W151311370C2780868729 @default.
• W151311370 hasConceptScore W151311370C2911091166 @default.
• W151311370 hasConceptScore W151311370C2991799789 @default.
• W151311370 hasConceptScore W151311370C61511704 @default.
• W151311370 hasConceptScore W151311370C71924100 @default.
• W151311370 hasConceptScore W151311370C8443397 @default.
• W151311370 hasConceptScore W151311370C90924648 @default.
• W151311370 hasIssue "2" @default.
• W151311370 hasLocation W1513113701 @default.
• W151311370 hasOpenAccess W151311370 @default.
• W151311370 hasPrimaryLocation W1513113701 @default.
• W151311370 hasRelatedWork W151311370 @default.
• W151311370 hasRelatedWork W1967657897 @default.
• W151311370 hasRelatedWork W2040694248 @default.
• W151311370 hasRelatedWork W2051488583 @default.
• W151311370 hasRelatedWork W2086470616 @default.
• W151311370 hasRelatedWork W2352517106 @default.
• W151311370 hasRelatedWork W2755644649 @default.
• W151311370 hasRelatedWork W2802508650 @default.
• W151311370 hasRelatedWork W4200380000 @default.
• W151311370 hasRelatedWork W4214759433 @default.
• W151311370 hasVolume "72" @default.
• W151311370 isParatext "false" @default.
• W151311370 isRetracted "false" @default.
• W151311370 magId "151311370" @default.
• W151311370 workType "article" @default.