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- W1513492098 abstract "More than 650,000 cases of pulmonary embolism (PE) are reported each year, resulting in an estimated 300,000 annual fatalities. This level of occurrence ranks PE as the third leading cause of death in the USA [ Laack TA, 2004; Tapson VF, 2008]. Multidetector CT (MDCT) pulmonary angiography has now largely replaced ventilation/perfusion scintigraphy and conventional pulmonary angiography for the evaluation of possible PE [Patel S,2003]. In 2007, MDCT pulmonary angiography was accepted as the reference standard for diagnosis of acute PE [Remy-Jardin M,2007]. However, conventional MDCT pulmonary angiography only provides morphological information and its ability to assess subsegmental pulmonary arteries is variable: sensitivities range from 37%–96%. The ability to assess subsegmental pulmonary arteries has increased with advances in MDCT technology. In the past, various CT techniques have been developed to evaluate the assessment of lung perfusion in patients with suspected PE. (1) Dynamic multi-section electron beam CT [Schoepf UJ,2000]. This perfusion-based CT technique had a scanning volume of 7.6 cm, required a long patient breathhold, and delivered a high additional radiation dose to the patient. (2) Color-coding the density of lung parenchyma in contrast-enhanced CTA [Wildberger JE,2001]. This technique is of limited use when lung diseases, such as groundglass opacities (e.g., in pulmonary edema or pneumonia) were present.′3′′A subtraction CTA technique of whole-thorax multi-detector CT scans acquired before and after intravenous contrast within a single breathhold. This technique was limited by a longer breathhold time, misregistration artifacts because of the mismatched unenhanced and contrast-enhanced scans, and additional radiation dose caused by the fact that an additional unenhanced scan had to be performed to assess the iodine distribution in the lung [Wildberger JE,2005]. Recently, DECT with different dual energy CT hardware (dual source CT and rapid kV switching technique) became available to simultaneously provide the functional and morphological information, overcoming the limitations of the above-mentioned CT" @default.
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- W1513492098 date "2012-03-14" @default.
- W1513492098 modified "2023-09-27" @default.
- W1513492098 title "Dual Source, Dual Energy Computed Tomography in Pulmonary Embolism" @default.
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- W1513492098 doi "https://doi.org/10.5772/31720" @default.
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