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• W1513855087 abstract "The aim of this study was to evaluate over expression of epidermal growth factor receptor (EGFR) gene in localized prostate cancers and determine its relation with clinical and pathological factors affecting the progression of the disease. Methods: In the tissue samples of the patients with prostate cancer undergoing radical prostatectomy, EGFR expression was evaluated by immunohistochemistry technique. Those with scores 2 and 3 were considered to be positive for the expression. The relation between gene expression and grade was evaluated by chi-square test. Results: Of 100 tissue samples evaluated, 80 and 20 had Gleason score (GS) 10, respectively. A total of 59 samples were positive for EGFR expression, of whom, 46 had GS 7 (P-value = 0.39). Forty patients had PSA 10 (P-value = 0.5). Conclusion: Fifty-nine percent of the patients with localized prostate cancer undergoing radical prostatectomy were EGFR positive. No significant relation was found between EGFR and grading (GS) or PSA." @default.
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• W1513855087 date "2010-12-31" @default.
• W1513855087 modified "2023-09-24" @default.
• W1513855087 title "Epidermal Growth Factor Receptor Gene in Prostate Cancer after Radical Prostatectomy" @default.
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