Matches in SemOpenAlex for { <https://semopenalex.org/work/W1514426224> ?p ?o ?g. }
- W1514426224 endingPage "222" @default.
- W1514426224 startingPage "210" @default.
- W1514426224 abstract "Plant methyl-DNA-binding proteins (MBDs), discovered by sequence homology to their animal counterparts, have not been well characterized at the physiological and functional levels. In order better to characterize the Arabidopsis AtMBD7 protein, unique in bearing three MBD domains, we used a yeast two-hybrid system to identify its partners. One of the interacting proteins we cloned is the Arabidopsis arginine methyltransferase 11 (AtPRMT11). Glutathione S-transferase pull-down and co-immunoprecipitation assays confirmed that the two proteins interact with each other and can be co-isolated. Using GFP fluorescence, we show that both AtMBD7 and AtPRMT11 are present in the nucleus. Further analyses revealed that AtPRMT11 acts as an arginine methyltransferase active on both histones and proteins of cellular extracts. The analysis of a T-DNA mutant line lacking AtPRMT11 mRNA revealed reduced levels of proteins with asymmetrically dimethylated arginines, suggesting that AtPRMT11, which is highly similar to mammalian PRMT1, is indeed a type I arginine methyltransferase. Further, AtMBD7 is a substrate for AtPRMT11, which post-translationally modifies the portion of the protein-containing C-terminal methylated DNA-binding domain. These results suggest the existence of a link between DNA methylation and arginine methylation." @default.
- W1514426224 created "2016-06-24" @default.
- W1514426224 creator A5012795704 @default.
- W1514426224 creator A5014569704 @default.
- W1514426224 creator A5022839754 @default.
- W1514426224 creator A5047614758 @default.
- W1514426224 creator A5058538051 @default.
- W1514426224 creator A5082552061 @default.
- W1514426224 date "2007-08-21" @default.
- W1514426224 modified "2023-10-16" @default.
- W1514426224 title "PRMT11: a new Arabidopsis MBD7 protein partner with arginine methyltransferase activity" @default.
- W1514426224 cites W1528728961 @default.
- W1514426224 cites W1550720320 @default.
- W1514426224 cites W1567517848 @default.
- W1514426224 cites W1608490912 @default.
- W1514426224 cites W1903792504 @default.
- W1514426224 cites W1945516621 @default.
- W1514426224 cites W1966077676 @default.
- W1514426224 cites W1974249897 @default.
- W1514426224 cites W1974714914 @default.
- W1514426224 cites W1976980117 @default.
- W1514426224 cites W1977032812 @default.
- W1514426224 cites W1978550291 @default.
- W1514426224 cites W1980020395 @default.
- W1514426224 cites W1985551321 @default.
- W1514426224 cites W1988754209 @default.
- W1514426224 cites W2001856542 @default.
- W1514426224 cites W2019072238 @default.
- W1514426224 cites W2019474060 @default.
- W1514426224 cites W2027652933 @default.
- W1514426224 cites W2029754586 @default.
- W1514426224 cites W2031797010 @default.
- W1514426224 cites W2032594275 @default.
- W1514426224 cites W2036245914 @default.
- W1514426224 cites W2038168145 @default.
- W1514426224 cites W2040741853 @default.
- W1514426224 cites W2044549899 @default.
- W1514426224 cites W2052668971 @default.
- W1514426224 cites W2055496814 @default.
- W1514426224 cites W2055598140 @default.
- W1514426224 cites W2057379290 @default.
- W1514426224 cites W2062806591 @default.
- W1514426224 cites W2066020764 @default.
- W1514426224 cites W2088201939 @default.
- W1514426224 cites W2091533776 @default.
- W1514426224 cites W2091658754 @default.
- W1514426224 cites W2092809155 @default.
- W1514426224 cites W2096846272 @default.
- W1514426224 cites W2097382368 @default.
- W1514426224 cites W2098115340 @default.
- W1514426224 cites W2098717784 @default.
- W1514426224 cites W2098848421 @default.
- W1514426224 cites W2104047605 @default.
- W1514426224 cites W2106993553 @default.
- W1514426224 cites W2111806638 @default.
- W1514426224 cites W2116278708 @default.
- W1514426224 cites W2117892897 @default.
- W1514426224 cites W2126371676 @default.
- W1514426224 cites W2129208603 @default.
- W1514426224 cites W2135152296 @default.
- W1514426224 cites W2143027433 @default.
- W1514426224 cites W2145830791 @default.
- W1514426224 cites W2147176162 @default.
- W1514426224 cites W2148685096 @default.
- W1514426224 cites W2149418407 @default.
- W1514426224 cites W2151960388 @default.
- W1514426224 cites W2152497434 @default.
- W1514426224 cites W2153111398 @default.
- W1514426224 cites W2154648145 @default.
- W1514426224 cites W2155563035 @default.
- W1514426224 cites W2156371750 @default.
- W1514426224 cites W2157503991 @default.
- W1514426224 cites W2157826971 @default.
- W1514426224 cites W2166612636 @default.
- W1514426224 cites W277139304 @default.
- W1514426224 doi "https://doi.org/10.1111/j.1365-313x.2007.03238.x" @default.
- W1514426224 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17711414" @default.
- W1514426224 hasPublicationYear "2007" @default.
- W1514426224 type Work @default.
- W1514426224 sameAs 1514426224 @default.
- W1514426224 citedByCount "35" @default.
- W1514426224 countsByYear W15144262242012 @default.
- W1514426224 countsByYear W15144262242013 @default.
- W1514426224 countsByYear W15144262242015 @default.
- W1514426224 countsByYear W15144262242017 @default.
- W1514426224 countsByYear W15144262242018 @default.
- W1514426224 countsByYear W15144262242019 @default.
- W1514426224 countsByYear W15144262242020 @default.
- W1514426224 countsByYear W15144262242021 @default.
- W1514426224 countsByYear W15144262242022 @default.
- W1514426224 countsByYear W15144262242023 @default.
- W1514426224 crossrefType "journal-article" @default.
- W1514426224 hasAuthorship W1514426224A5012795704 @default.
- W1514426224 hasAuthorship W1514426224A5014569704 @default.
- W1514426224 hasAuthorship W1514426224A5022839754 @default.
- W1514426224 hasAuthorship W1514426224A5047614758 @default.
- W1514426224 hasAuthorship W1514426224A5058538051 @default.
- W1514426224 hasAuthorship W1514426224A5082552061 @default.