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- W1514668105 abstract "Publisher Summary This chapter describes the diversity of lipids, methods to study intra- and inter-membrane lipid transport, and lipid transport processes. The lipid composition of bacteria, fungi, lower animal eucaryotes, and higher animal eucaryotes reveals that within each organism or cell there is a substantial amount of lipid diversity. The chapter also presents various approaches for evaluating the intra- and inter-membrane lipid transport, such as the use of fluorescent probes, spin labeled analogs, and asymmetric chemical modification of membranes. The ability of proteins to transfer lipids from accessible membrane compartments has made them useful tools for transplanting lipids into and out of membranes and probing the transbilayer movement of phospholipids. It is clear that for intra-membrane lipid translocation processes both ATP dependent and ATP independent mechanisms exist. Thus, lipid transport is a highly complex process exhibiting little redundancy, and a number of problems that need to be addressed in the future are now readily apparent, including mechanistic definition of the ATP requirement for phosphatidylserine transport to the mitochondria or clarification of the in vivo role of phospholipid transfer proteins." @default.
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- W1514668105 date "1991-01-01" @default.
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- W1514668105 title "Chapter 17 Lipid assembly into cell membranes" @default.
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- W1514668105 doi "https://doi.org/10.1016/s0167-7306(08)60345-2" @default.
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