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- W1514707112 abstract "This work describes the architecture of an agent based computer model that simulates the autoimmune response in Type 1 diabetes in a three-dimensional cubic volume representing a fragment of pancreas of a mouse. Immune cells and β-cells are modeled as agents, making the abstraction of one cell — one agent. We present our preliminary results for the interactions between β-cell agents and macrophage agents and a model of cell motility in the continuous three-dimensional volume. This agent-based approach allows implementing multi-scale computational modeling capturing subcellular characteristics into cell agents and obtaining outcomes from agent populations at tissue and systemic levels." @default.
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- W1514707112 date "2012-06-20" @default.
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- W1514707112 title "Definition of an agent-based model of the autoimmune response in Type 1 diabetes" @default.
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