FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1514968045> ?p ?o ?g. }

• W1514968045 endingPage "866" @default.
• W1514968045 startingPage "857" @default.
• W1514968045 abstract "While it is evident that Alzheimer's disease is associated with disturbed sleep and circadian rhythms, the extent to which such changes are evident in older people 'at risk' of developing dementia is unknown.In this study, we aimed to determine whether patients with mild cognitive impairment (MCI) demonstrated significant alterations in the timing of melatonin secretion onset and amount, as well as sleep architecture.Thirty patients with MCI and 28 age-matched controls underwent psychiatric, medical, and neuropsychological assessment, followed by overnight polysomnography and dim light melatonin onset assessment. Participants also performed an episodic memory task while in the laboratory. Dim light melatonin onset was computed using a standardized algorithm, and area under the curve was computed for melatonin secretion. Sleep architecture measures including wake after sleep onset and latency to rapid eye movement sleep were derived.Patients with MCI had advanced timing of their melatonin secretion onset relative to controls, but the levels of melatonin secreted did not differ between groups. The MCI group also had greater wake after sleep onset and increased rapid eye movement sleep latency. There were differential associations between dim light melatonin onset and cognition between the two groups, with earlier dim light melatonin onset being associated with poorer memory performance in MCI patients.Circadian misalignment and sleep disruption is evident in patients with MCI, and is consistent with changes observed in Alzheimer's disease. Such findings could be a marker for disease trajectory, and may even be implicated in disease pathogenesis." @default.
• W1514968045 created "2016-06-24" @default.
• W1514968045 creator A5023737973 @default.
• W1514968045 creator A5027292482 @default.
• W1514968045 creator A5060784831 @default.
• W1514968045 creator A5069078473 @default.
• W1514968045 creator A5069129362 @default.
• W1514968045 creator A5074694026 @default.
• W1514968045 creator A5077825658 @default.
• W1514968045 creator A5086248686 @default.
• W1514968045 date "2013-12-10" @default.
• W1514968045 modified "2023-10-13" @default.
• W1514968045 title "Circadian Misalignment and Sleep Disruption in Mild Cognitive Impairment" @default.
• W1514968045 cites W145630688 @default.
• W1514968045 cites W1492774743 @default.
• W1514968045 cites W1509106161 @default.
• W1514968045 cites W1626398964 @default.
• W1514968045 cites W1844583257 @default.
• W1514968045 cites W1847168837 @default.
• W1514968045 cites W1926588156 @default.
• W1514968045 cites W1968838957 @default.
• W1514968045 cites W197066864 @default.
• W1514968045 cites W1973728640 @default.
• W1514968045 cites W1991021935 @default.
• W1514968045 cites W1999900894 @default.
• W1514968045 cites W2013431267 @default.
• W1514968045 cites W2019690505 @default.
• W1514968045 cites W2033264902 @default.
• W1514968045 cites W2038442817 @default.
• W1514968045 cites W2040239884 @default.
• W1514968045 cites W2042938678 @default.
• W1514968045 cites W2044315129 @default.
• W1514968045 cites W2045101379 @default.
• W1514968045 cites W2046135723 @default.
• W1514968045 cites W2058525260 @default.
• W1514968045 cites W2066052331 @default.
• W1514968045 cites W2071478700 @default.
• W1514968045 cites W2079322258 @default.
• W1514968045 cites W2084071041 @default.
• W1514968045 cites W2086162146 @default.
• W1514968045 cites W2087744632 @default.
• W1514968045 cites W2097750812 @default.
• W1514968045 cites W2098244868 @default.
• W1514968045 cites W2100322905 @default.
• W1514968045 cites W2103987983 @default.
• W1514968045 cites W2106995358 @default.
• W1514968045 cites W2132996891 @default.
• W1514968045 cites W2142393219 @default.
• W1514968045 cites W2142410239 @default.
• W1514968045 cites W2149514113 @default.
• W1514968045 cites W2149723353 @default.
• W1514968045 cites W2151445031 @default.
• W1514968045 cites W2153476264 @default.
• W1514968045 cites W2156204070 @default.
• W1514968045 cites W2172788585 @default.
• W1514968045 cites W2410773806 @default.
• W1514968045 cites W2413448243 @default.
• W1514968045 cites W2810887452 @default.
• W1514968045 cites W3022302886 @default.
• W1514968045 cites W46432011 @default.
• W1514968045 cites W1511275384 @default.
• W1514968045 doi "https://doi.org/10.3233/jad-131217" @default.
• W1514968045 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24100124" @default.
• W1514968045 hasPublicationYear "2013" @default.
• W1514968045 type Work @default.
• W1514968045 sameAs 1514968045 @default.
• W1514968045 citedByCount "93" @default.
• W1514968045 countsByYear W15149680452014 @default.
• W1514968045 countsByYear W15149680452015 @default.
• W1514968045 countsByYear W15149680452016 @default.
• W1514968045 countsByYear W15149680452017 @default.
• W1514968045 countsByYear W15149680452018 @default.
• W1514968045 countsByYear W15149680452019 @default.
• W1514968045 countsByYear W15149680452020 @default.
• W1514968045 countsByYear W15149680452021 @default.
• W1514968045 countsByYear W15149680452022 @default.
• W1514968045 countsByYear W15149680452023 @default.
• W1514968045 crossrefType "journal-article" @default.
• W1514968045 hasAuthorship W1514968045A5023737973 @default.
• W1514968045 hasAuthorship W1514968045A5027292482 @default.
• W1514968045 hasAuthorship W1514968045A5060784831 @default.
• W1514968045 hasAuthorship W1514968045A5069078473 @default.
• W1514968045 hasAuthorship W1514968045A5069129362 @default.
• W1514968045 hasAuthorship W1514968045A5074694026 @default.
• W1514968045 hasAuthorship W1514968045A5077825658 @default.
• W1514968045 hasAuthorship W1514968045A5086248686 @default.
• W1514968045 hasConcept C111919701 @default.
• W1514968045 hasConcept C118552586 @default.
• W1514968045 hasConcept C121446783 @default.
• W1514968045 hasConcept C126322002 @default.
• W1514968045 hasConcept C134018914 @default.
• W1514968045 hasConcept C15744967 @default.
• W1514968045 hasConcept C2775841894 @default.
• W1514968045 hasConcept C2778182776 @default.
• W1514968045 hasConcept C2778205975 @default.
• W1514968045 hasConcept C2779134260 @default.
• W1514968045 hasConcept C2779483572 @default.
• W1514968045 hasConcept C2781210498 @default.

• next