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- W1515676898 abstract "For over 50 years, antipsychotics have been the most commonly used drugs for the treatment of mania. Haloperidol has been one of the most widely used. The clinical trials of new generation antipsychotics in mania, sponsored by the pharmaceutical manufacturers, have answered many important questions about bipolar disorder that were unresolved. In particular, they have shown that antipsychotics generally have specific antimanic properties that are independent of sedation or psychosis. The speed of action and size of effect of antipsychotics makes them especially useful for the control of emergent (hypomanic) symptoms and for acute tranquillization in mania. None of the atypicals has proved more effective than haloperidol in reducing manic symptoms, some of them are less so; but all produce fewer extrapyramidal side effects than haloperidol and may therefore be more acceptable to patients. This chapter reviews the evidence concerning the use of first generation antipsychotics in mania." @default.
- W1515676898 created "2016-06-24" @default.
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- W1515676898 date "2011-04-13" @default.
- W1515676898 modified "2023-09-26" @default.
- W1515676898 title "Haloperidol and Other First Generation Antipsychotics in Mania" @default.
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- W1515676898 doi "https://doi.org/10.1002/9780470975114.ch7" @default.
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