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- W1516294369 abstract "The Middle East respiratory syndrome coronavirus (MERS-CoV) is a novel virus which was first isolated in April 2012 from a patient with severe acute respiratory infection in Jordan. As of September 7, 2013, there have been 114 cases of laboratory-confirmed infection with MERS-CoV in the Middle East (predominantly Saudi Arabia) and Europe, including 54 deaths. All reported cases outside of the Middle East have occurred in recent travelers to the Middle East or their close contacts, and the majority of fatalities have occurred in individuals with underlying medical conditions. Much remains unknown about the epidemiology of MERS-CoV, including the exact mode of transmission, number of asymptomatic or mildly symptomatic cases, and presence of an animal reservoir. Transmission seems to occur primarily among household contacts and has also been reported in health care facilities, including an outbreak with 23 confirmed and 11 probable cases in four health care facilities in the eastern province of Saudi Arabia during April and May 2013. The incubation period of MERSCoV is thought to be up to 14 days, which can facilitate spread of the virus when infected individuals travel prior to becoming symptomatic. At present, there is no available vaccine for MERS-CoV, and treatment consists of supportive measures only. However, due to lack of sustained transmission in communities, the World Health Organization (WHO) does not consider MERS-CoV to be a public health emergency at this time. The Hajj pilgrimage to Mecca, Saudi Arabia is one of the largest mass gatherings in the world, drawing more than three million Muslims from around the globe each year. Transmission of communicable diseases during mass gatherings such as the Hajj has become an increasing concern, as such gatherings bring individuals from all over the world into close contact for days at a time. In fact, “mass gathering medicine” has recently emerged as a medical specialty focused on preventing and treating illness and injury during such events. In order to prevent transmission of communicable diseases during the Hajj, the Saudi Arabian Ministry of Health currently requires certain vaccines (for yellow fever, meningococcal meningitis, and poliomyelitis) depending on a traveler's country of origin. Influenza vaccination, strict attention to personal hygiene (especially handwashing and cough etiquette), and avoidance of unnecessary contact with animals are also strongly recommended. Despite reassurance by the WHO that the risk of infection with MERS-CoV among those traveling to Saudi Arabia this October for the Hajj is very low, there remains significant concern among the international community about the poDepartment of Medicine, Division of Infectious Diseases, Weill Cornell, Medical College, New York, NY, USA" @default.
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- W1516294369 date "2013-10-01" @default.
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- W1516294369 title "Middle East respiratory syndrome coronavirus and the upcoming Hajj." @default.
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