FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1516610787> ?p ?o ?g. }

• W1516610787 endingPage "5201" @default.
• W1516610787 startingPage "5195" @default.
• W1516610787 abstract "The specificity of the Escherichia coli RuvC Holliday junction resolvase has been investigated in vitro. RuvC protein cleaves synthetic DNA substrates that model three- or four-stranded recombination intermediates but fails to act upon Y junctions, G/A mismatches, heterologous loop structures, or two-stranded branched junctions. RuvC therefore differs from endonuclease VII of bacteriophage T4 which exhibits broad range specificity. Using related three- and four-stranded synthetic DNA junctions, we show that RuvC cleaves both junctions at the same DNA sequence and requires a region of homology at the junction point. The action of RuvC on three- and four-stranded recombination intermediates made by RecA was also investigated. We found that RuvC fails to resolve three-stranded intermediates in the presence of RecA, although four-stranded intermediates are resolved under the same conditions. However, both three- and four-stranded intermediates are substrates for the nuclease after removal of RecA. We interpret these differences in terms of the contiguity of the RecA nucleoprotein filament which may, under certain conditions, limit access to the Holliday junction resolvase." @default.
• W1516610787 created "2016-06-24" @default.
• W1516610787 creator A5034074780 @default.
• W1516610787 creator A5054117046 @default.
• W1516610787 date "1994-02-01" @default.
• W1516610787 modified "2023-10-06" @default.
• W1516610787 title "Substrate specificity of the Escherichia coli RuvC protein. Resolution of three- and four-stranded recombination intermediates." @default.
• W1516610787 cites W1521689319 @default.
• W1516610787 cites W1552691165 @default.
• W1516610787 cites W1553481351 @default.
• W1516610787 cites W1558516755 @default.
• W1516610787 cites W1571933804 @default.
• W1516610787 cites W1582967964 @default.
• W1516610787 cites W1589118081 @default.
• W1516610787 cites W182692292 @default.
• W1516610787 cites W1848002250 @default.
• W1516610787 cites W1863020992 @default.
• W1516610787 cites W1972852754 @default.
• W1516610787 cites W1973288261 @default.
• W1516610787 cites W1979561196 @default.
• W1516610787 cites W1983727450 @default.
• W1516610787 cites W1985290656 @default.
• W1516610787 cites W1986115296 @default.
• W1516610787 cites W1986799468 @default.
• W1516610787 cites W1992309825 @default.
• W1516610787 cites W1999746794 @default.
• W1516610787 cites W2019146077 @default.
• W1516610787 cites W2028622989 @default.
• W1516610787 cites W2038093678 @default.
• W1516610787 cites W2038390368 @default.
• W1516610787 cites W2039163149 @default.
• W1516610787 cites W2039646812 @default.
• W1516610787 cites W2041074390 @default.
• W1516610787 cites W2043810088 @default.
• W1516610787 cites W2050149166 @default.
• W1516610787 cites W2057720119 @default.
• W1516610787 cites W2071662270 @default.
• W1516610787 cites W2075925680 @default.
• W1516610787 cites W2132373675 @default.
• W1516610787 cites W2134511156 @default.
• W1516610787 cites W2137723211 @default.
• W1516610787 cites W2149883538 @default.
• W1516610787 cites W2159075866 @default.
• W1516610787 cites W2160393299 @default.
• W1516610787 cites W2171935042 @default.
• W1516610787 cites W42185755 @default.
• W1516610787 cites W4323517714 @default.
• W1516610787 doi "https://doi.org/10.1016/s0021-9258(17)37674-3" @default.
• W1516610787 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8106501" @default.
• W1516610787 hasPublicationYear "1994" @default.
• W1516610787 type Work @default.
• W1516610787 sameAs 1516610787 @default.
• W1516610787 citedByCount "70" @default.
• W1516610787 countsByYear W15166107872012 @default.
• W1516610787 countsByYear W15166107872013 @default.
• W1516610787 countsByYear W15166107872014 @default.
• W1516610787 countsByYear W15166107872015 @default.
• W1516610787 countsByYear W15166107872016 @default.
• W1516610787 countsByYear W15166107872017 @default.
• W1516610787 countsByYear W15166107872021 @default.
• W1516610787 countsByYear W15166107872022 @default.
• W1516610787 crossrefType "journal-article" @default.
• W1516610787 hasAuthorship W1516610787A5034074780 @default.
• W1516610787 hasAuthorship W1516610787A5054117046 @default.
• W1516610787 hasBestOaLocation W15166107871 @default.
• W1516610787 hasConcept C104317684 @default.
• W1516610787 hasConcept C12554922 @default.
• W1516610787 hasConcept C138268822 @default.
• W1516610787 hasConcept C154945302 @default.
• W1516610787 hasConcept C156695909 @default.
• W1516610787 hasConcept C181199279 @default.
• W1516610787 hasConcept C185592680 @default.
• W1516610787 hasConcept C18903297 @default.
• W1516610787 hasConcept C2777289219 @default.
• W1516610787 hasConcept C2994592520 @default.
• W1516610787 hasConcept C41008148 @default.
• W1516610787 hasConcept C547475151 @default.
• W1516610787 hasConcept C55493867 @default.
• W1516610787 hasConcept C86803240 @default.
• W1516610787 hasConceptScore W1516610787C104317684 @default.
• W1516610787 hasConceptScore W1516610787C12554922 @default.
• W1516610787 hasConceptScore W1516610787C138268822 @default.
• W1516610787 hasConceptScore W1516610787C154945302 @default.
• W1516610787 hasConceptScore W1516610787C156695909 @default.
• W1516610787 hasConceptScore W1516610787C181199279 @default.
• W1516610787 hasConceptScore W1516610787C185592680 @default.
• W1516610787 hasConceptScore W1516610787C18903297 @default.
• W1516610787 hasConceptScore W1516610787C2777289219 @default.
• W1516610787 hasConceptScore W1516610787C2994592520 @default.
• W1516610787 hasConceptScore W1516610787C41008148 @default.
• W1516610787 hasConceptScore W1516610787C547475151 @default.
• W1516610787 hasConceptScore W1516610787C55493867 @default.
• W1516610787 hasConceptScore W1516610787C86803240 @default.
• W1516610787 hasIssue "7" @default.
• W1516610787 hasLocation W15166107871 @default.
• W1516610787 hasOpenAccess W1516610787 @default.
• W1516610787 hasPrimaryLocation W15166107871 @default.
• W1516610787 hasRelatedWork W1516610787 @default.

• next