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- W1516926758 abstract "In the 1980s, when maintenance charges for cats and dogs rose to prohibitive levels, cardiovascular investigators searched for a more economical alternative that exhibited cardiac and vascular characteristics in common with man. The ferret became recognized as a viable alternative to the classical animal species. Ferret myocardium exhibits a positive force– frequency relationship, analogous to man. Cardiac disease in pet ferrets is common and includes dilated cardiomyopathy, arrhythmias, and acquired valvular disease. A study revealed that ferrets were more sensitive to aspirin than rats. Ferrets provide a reproducible model of ischemia that has the advantage of a short experimental preparation to study ischemic injury. Ferrets are an excellent source of smooth muscle from multiple vascular beds for in vivo and in vitro experimentation. The use of ferret preparations proved instrumental for discovery of unique calcium-independent signaling pathways in vascular smooth muscle." @default.
- W1516926758 created "2016-06-24" @default.
- W1516926758 creator A5089576007 @default.
- W1516926758 date "2014-03-28" @default.
- W1516926758 modified "2023-10-18" @default.
- W1516926758 title "Use of the Ferret in Cardiovascular Research" @default.
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- W1516926758 doi "https://doi.org/10.1002/9781118782699.ch27" @default.
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