FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1517278511> ?p ?o ?g. }

• W1517278511 abstract "The gene for tRNAMet1 from Xenopus oocytes was transcribed in a cell free system with components isolated from a HeLa cell-free extract. It was found that, apart from the established assembly of transcription factors IIIB and IIIC on tRNA genes into stable transcription complexes, these factors can also associate with the enzyme in the absence of DNA to form a functional polymerase III complex. These complexes can be isolated in a highly active form from the bulk of other cellular proteins by mild methods such as gel filtration or density gradient centrifugation. When associated with RNA polymerase III into a functional complex, the transcription factors IIIB and IIIC can clearly be differentiated from free transcription factors, which individually display a much lower relative molecular mass. The polymerase complexes are stable against 1 M KCl, rendering unlikely that they represent fortuitous aggregates including RNA polymerase III and transcription factors IIIB and IIIC. These complexes are sensitive to dilution and, whereas transcription factor IIIC binds to the enzyme more tightly, factor IIIB tends to leak from the complex upon dilution of the protein concentration. From these results it is clear that in addition to their function as DNA-binding protein(s), transcription factors IIIB and IIIC can directly interact with RNA polymerase III without prior binding to the promoter region of the gene to be transcribed." @default.
• W1517278511 created "2016-06-24" @default.
• W1517278511 creator A5000115198 @default.
• W1517278511 creator A5029172959 @default.
• W1517278511 creator A5041916369 @default.
• W1517278511 date "1986-01-01" @default.
• W1517278511 modified "2023-10-05" @default.
• W1517278511 title "Association of RNA polymerase III with transcription factors in the absence of DNA." @default.
• W1517278511 cites W1482729845 @default.
• W1517278511 cites W1501158542 @default.
• W1517278511 cites W1501793516 @default.
• W1517278511 cites W1509132667 @default.
• W1517278511 cites W1522226780 @default.
• W1517278511 cites W1535489458 @default.
• W1517278511 cites W1561042132 @default.
• W1517278511 cites W1579745531 @default.
• W1517278511 cites W1587278982 @default.
• W1517278511 cites W1597915623 @default.
• W1517278511 cites W1750256253 @default.
• W1517278511 cites W1864119499 @default.
• W1517278511 cites W2006624258 @default.
• W1517278511 cites W2038278029 @default.
• W1517278511 cites W2052125048 @default.
• W1517278511 cites W2062531827 @default.
• W1517278511 cites W2068183546 @default.
• W1517278511 cites W2081630434 @default.
• W1517278511 cites W2096628378 @default.
• W1517278511 cites W2172343655 @default.
• W1517278511 cites W2397440610 @default.
• W1517278511 cites W41481939 @default.
• W1517278511 cites W4293247451 @default.
• W1517278511 cites W67580660 @default.
• W1517278511 doi "https://doi.org/10.1016/s0021-9258(17)36107-0" @default.
• W1517278511 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3632975" @default.
• W1517278511 hasPublicationYear "1986" @default.
• W1517278511 type Work @default.
• W1517278511 sameAs 1517278511 @default.
• W1517278511 citedByCount "28" @default.
• W1517278511 crossrefType "journal-article" @default.
• W1517278511 hasAuthorship W1517278511A5000115198 @default.
• W1517278511 hasAuthorship W1517278511A5029172959 @default.
• W1517278511 hasAuthorship W1517278511A5041916369 @default.
• W1517278511 hasBestOaLocation W15172785111 @default.
• W1517278511 hasConcept C101762097 @default.
• W1517278511 hasConcept C104317684 @default.
• W1517278511 hasConcept C105208137 @default.
• W1517278511 hasConcept C138885662 @default.
• W1517278511 hasConcept C144825837 @default.
• W1517278511 hasConcept C150194340 @default.
• W1517278511 hasConcept C153911025 @default.
• W1517278511 hasConcept C154816499 @default.
• W1517278511 hasConcept C156951783 @default.
• W1517278511 hasConcept C172768829 @default.
• W1517278511 hasConcept C179926584 @default.
• W1517278511 hasConcept C185592680 @default.
• W1517278511 hasConcept C188740287 @default.
• W1517278511 hasConcept C196117886 @default.
• W1517278511 hasConcept C25281209 @default.
• W1517278511 hasConcept C2776449523 @default.
• W1517278511 hasConcept C41258723 @default.
• W1517278511 hasConcept C41895202 @default.
• W1517278511 hasConcept C552990157 @default.
• W1517278511 hasConcept C55493867 @default.
• W1517278511 hasConcept C64350747 @default.
• W1517278511 hasConcept C67705224 @default.
• W1517278511 hasConcept C70916841 @default.
• W1517278511 hasConcept C82381507 @default.
• W1517278511 hasConcept C86803240 @default.
• W1517278511 hasConceptScore W1517278511C101762097 @default.
• W1517278511 hasConceptScore W1517278511C104317684 @default.
• W1517278511 hasConceptScore W1517278511C105208137 @default.
• W1517278511 hasConceptScore W1517278511C138885662 @default.
• W1517278511 hasConceptScore W1517278511C144825837 @default.
• W1517278511 hasConceptScore W1517278511C150194340 @default.
• W1517278511 hasConceptScore W1517278511C153911025 @default.
• W1517278511 hasConceptScore W1517278511C154816499 @default.
• W1517278511 hasConceptScore W1517278511C156951783 @default.
• W1517278511 hasConceptScore W1517278511C172768829 @default.
• W1517278511 hasConceptScore W1517278511C179926584 @default.
• W1517278511 hasConceptScore W1517278511C185592680 @default.
• W1517278511 hasConceptScore W1517278511C188740287 @default.
• W1517278511 hasConceptScore W1517278511C196117886 @default.
• W1517278511 hasConceptScore W1517278511C25281209 @default.
• W1517278511 hasConceptScore W1517278511C2776449523 @default.
• W1517278511 hasConceptScore W1517278511C41258723 @default.
• W1517278511 hasConceptScore W1517278511C41895202 @default.
• W1517278511 hasConceptScore W1517278511C552990157 @default.
• W1517278511 hasConceptScore W1517278511C55493867 @default.
• W1517278511 hasConceptScore W1517278511C64350747 @default.
• W1517278511 hasConceptScore W1517278511C67705224 @default.
• W1517278511 hasConceptScore W1517278511C70916841 @default.
• W1517278511 hasConceptScore W1517278511C82381507 @default.
• W1517278511 hasConceptScore W1517278511C86803240 @default.
• W1517278511 hasLocation W15172785111 @default.
• W1517278511 hasOpenAccess W1517278511 @default.
• W1517278511 hasPrimaryLocation W15172785111 @default.
• W1517278511 hasRelatedWork W1482729845 @default.
• W1517278511 hasRelatedWork W1487010108 @default.
• W1517278511 hasRelatedWork W1496403573 @default.
• W1517278511 hasRelatedWork W1506876043 @default.

• next