Matches in SemOpenAlex for { <https://semopenalex.org/work/W1517355513> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W1517355513 endingPage "106" @default.
- W1517355513 startingPage "97" @default.
- W1517355513 abstract "Nasopharyngeal carcinoma (NPC) is a malignancy with high incidence in Southern China and South-East Asia. Etiology studies indicate that chemical carcinogen promoters, such as 12-O-tetradecanoylphorbol-13-acetate (TPA), are important factors causing NPC development. However, the mechanism of the TPA effect on NPC remains unclear. In the present study, cells from a poorly differentiated squamous cell carcinoma NPC cell line, CNE2, were stimulated by TPA and proteomics technology was carried out to find protein discrepancies between control and TPA-treated cells. Results revealed that TPA treatment in CNE2 cells could upregulate the expression of triosephosphate isomerase and 14-3-3 protein sigma and downregulate the expression of reticulocalbin 1 precursor, nucleophosmin, mitochondrial matrix protein pl precursor, and stathmin. The changes in the expression of these genes suggested that TPA induced CNE2 cells to antiproliferation and to apoptosis, which was confirmed by subsequent apoptosis detection. Therefore, the effects of TPA on nasopharyngeal carcinoma cells were distinct from the effects on primary epithelial cells and we suggest reasons for these differences." @default.
- W1517355513 created "2016-06-24" @default.
- W1517355513 creator A5011576432 @default.
- W1517355513 creator A5014205941 @default.
- W1517355513 creator A5043631132 @default.
- W1517355513 creator A5060881370 @default.
- W1517355513 creator A5077681132 @default.
- W1517355513 creator A5087690985 @default.
- W1517355513 date "2005-01-01" @default.
- W1517355513 modified "2023-09-28" @default.
- W1517355513 title "Proteomics-based Identification of Proteins with Altered Expression Induced by 12-O-Tetradecanoylphorbol 13-acetate in Nasopharyngeal Carcinoma CNE2 Cells" @default.
- W1517355513 hasPublicationYear "2005" @default.
- W1517355513 type Work @default.
- W1517355513 sameAs 1517355513 @default.
- W1517355513 citedByCount "0" @default.
- W1517355513 crossrefType "journal-article" @default.
- W1517355513 hasAuthorship W1517355513A5011576432 @default.
- W1517355513 hasAuthorship W1517355513A5014205941 @default.
- W1517355513 hasAuthorship W1517355513A5043631132 @default.
- W1517355513 hasAuthorship W1517355513A5060881370 @default.
- W1517355513 hasAuthorship W1517355513A5077681132 @default.
- W1517355513 hasAuthorship W1517355513A5087690985 @default.
- W1517355513 hasConcept C104317684 @default.
- W1517355513 hasConcept C126322002 @default.
- W1517355513 hasConcept C127561419 @default.
- W1517355513 hasConcept C153911025 @default.
- W1517355513 hasConcept C185592680 @default.
- W1517355513 hasConcept C190283241 @default.
- W1517355513 hasConcept C195794163 @default.
- W1517355513 hasConcept C2777168633 @default.
- W1517355513 hasConcept C2778654611 @default.
- W1517355513 hasConcept C2778997737 @default.
- W1517355513 hasConcept C3017695315 @default.
- W1517355513 hasConcept C502942594 @default.
- W1517355513 hasConcept C509974204 @default.
- W1517355513 hasConcept C54355233 @default.
- W1517355513 hasConcept C55493867 @default.
- W1517355513 hasConcept C62478195 @default.
- W1517355513 hasConcept C71924100 @default.
- W1517355513 hasConcept C81885089 @default.
- W1517355513 hasConcept C86803240 @default.
- W1517355513 hasConcept C95444343 @default.
- W1517355513 hasConceptScore W1517355513C104317684 @default.
- W1517355513 hasConceptScore W1517355513C126322002 @default.
- W1517355513 hasConceptScore W1517355513C127561419 @default.
- W1517355513 hasConceptScore W1517355513C153911025 @default.
- W1517355513 hasConceptScore W1517355513C185592680 @default.
- W1517355513 hasConceptScore W1517355513C190283241 @default.
- W1517355513 hasConceptScore W1517355513C195794163 @default.
- W1517355513 hasConceptScore W1517355513C2777168633 @default.
- W1517355513 hasConceptScore W1517355513C2778654611 @default.
- W1517355513 hasConceptScore W1517355513C2778997737 @default.
- W1517355513 hasConceptScore W1517355513C3017695315 @default.
- W1517355513 hasConceptScore W1517355513C502942594 @default.
- W1517355513 hasConceptScore W1517355513C509974204 @default.
- W1517355513 hasConceptScore W1517355513C54355233 @default.
- W1517355513 hasConceptScore W1517355513C55493867 @default.
- W1517355513 hasConceptScore W1517355513C62478195 @default.
- W1517355513 hasConceptScore W1517355513C71924100 @default.
- W1517355513 hasConceptScore W1517355513C81885089 @default.
- W1517355513 hasConceptScore W1517355513C86803240 @default.
- W1517355513 hasConceptScore W1517355513C95444343 @default.
- W1517355513 hasIssue "2" @default.
- W1517355513 hasLocation W15173555131 @default.
- W1517355513 hasOpenAccess W1517355513 @default.
- W1517355513 hasPrimaryLocation W15173555131 @default.
- W1517355513 hasRelatedWork W108784086 @default.
- W1517355513 hasRelatedWork W1981843959 @default.
- W1517355513 hasRelatedWork W1991912899 @default.
- W1517355513 hasRelatedWork W1995375042 @default.
- W1517355513 hasRelatedWork W2005269459 @default.
- W1517355513 hasRelatedWork W2021222768 @default.
- W1517355513 hasRelatedWork W2023983577 @default.
- W1517355513 hasRelatedWork W2064086023 @default.
- W1517355513 hasRelatedWork W2089374997 @default.
- W1517355513 hasRelatedWork W2109327605 @default.
- W1517355513 hasRelatedWork W2117903701 @default.
- W1517355513 hasRelatedWork W2142337569 @default.
- W1517355513 hasRelatedWork W2327756460 @default.
- W1517355513 hasRelatedWork W2331950007 @default.
- W1517355513 hasRelatedWork W2406997352 @default.
- W1517355513 hasRelatedWork W2502832630 @default.
- W1517355513 hasRelatedWork W2570036142 @default.
- W1517355513 hasRelatedWork W2768185191 @default.
- W1517355513 hasRelatedWork W2888658933 @default.
- W1517355513 hasRelatedWork W67080933 @default.
- W1517355513 hasVolume "37" @default.
- W1517355513 isParatext "false" @default.
- W1517355513 isRetracted "false" @default.
- W1517355513 magId "1517355513" @default.
- W1517355513 workType "article" @default.