Matches in SemOpenAlex for { <https://semopenalex.org/work/W1517555762> ?p ?o ?g. }
Showing items 1 to 69 of
69
with 100 items per page.
- W1517555762 abstract "Current study was aimed to investigate antioxidant and hepatoprotective effects of germinated andfermented soybean extract (GFSE) on tert-butyl hydroperoxide(t-BHP)–induced oxidative stress in HepG2 cell and rat liver. t-BHP-induced reactive oxygen species (ROS) production was significantly lowered by GFSE. The ROS reduction was associated with mRNA levels those are down-regulated nicotinamide adenine dinucleotide phosphate-oxidase 4 (NOX4), a pro-oxidant enzyme, and up-regulated anti-oxidant enzymes such as catalase, superoxide dismuatase (SOD), glutathione peroxidase (Gpx), and glutathione reductase (GR) in the liver. In addition, mRNA level of antioxidant enzymes those are related to the enhancement of enzymatic activities of SOD, catalase, and glutathione-S-transferase (GST) was also significantly increased. This antioxidant effect of GFSE was connected to the reduction of MDA (malondialdehyde) levels as well as the increase of glutathione (GSH) levels in the liver. Furthermore, GFS was shown to decrease the serum level of clinical markers for the liver function such as ALT (alanine aminotransferase), AST (Aspartate aminotransferase), and total cholesterol. These effects of GFSE were also confirmed by histopathological analyses. This work was supported by “Food Functionality Evaluation program” under the Ministry of Agriculture, Food and Rural Affairs and partly Korea Food Research Institute." @default.
- W1517555762 created "2016-06-24" @default.
- W1517555762 creator A5032711040 @default.
- W1517555762 creator A5041669433 @default.
- W1517555762 creator A5079848254 @default.
- W1517555762 date "2015-04-01" @default.
- W1517555762 modified "2023-10-18" @default.
- W1517555762 title "Protective Effect of Germinated and Fermented Soybean Extract Against tert ‐butyl Hydroperoxide‐Induced Hepatotoxicity in the Rats" @default.
- W1517555762 doi "https://doi.org/10.1096/fasebj.29.1_supplement.lb343" @default.
- W1517555762 hasPublicationYear "2015" @default.
- W1517555762 type Work @default.
- W1517555762 sameAs 1517555762 @default.
- W1517555762 citedByCount "0" @default.
- W1517555762 crossrefType "journal-article" @default.
- W1517555762 hasAuthorship W1517555762A5032711040 @default.
- W1517555762 hasAuthorship W1517555762A5041669433 @default.
- W1517555762 hasAuthorship W1517555762A5079848254 @default.
- W1517555762 hasConcept C165069038 @default.
- W1517555762 hasConcept C181199279 @default.
- W1517555762 hasConcept C185592680 @default.
- W1517555762 hasConcept C2775838275 @default.
- W1517555762 hasConcept C2776151105 @default.
- W1517555762 hasConcept C2777989768 @default.
- W1517555762 hasConcept C2778004101 @default.
- W1517555762 hasConcept C2778401633 @default.
- W1517555762 hasConcept C2778760513 @default.
- W1517555762 hasConcept C2778979269 @default.
- W1517555762 hasConcept C38485361 @default.
- W1517555762 hasConcept C48349386 @default.
- W1517555762 hasConcept C538909803 @default.
- W1517555762 hasConcept C55493867 @default.
- W1517555762 hasConcept C86803240 @default.
- W1517555762 hasConcept C98274493 @default.
- W1517555762 hasConceptScore W1517555762C165069038 @default.
- W1517555762 hasConceptScore W1517555762C181199279 @default.
- W1517555762 hasConceptScore W1517555762C185592680 @default.
- W1517555762 hasConceptScore W1517555762C2775838275 @default.
- W1517555762 hasConceptScore W1517555762C2776151105 @default.
- W1517555762 hasConceptScore W1517555762C2777989768 @default.
- W1517555762 hasConceptScore W1517555762C2778004101 @default.
- W1517555762 hasConceptScore W1517555762C2778401633 @default.
- W1517555762 hasConceptScore W1517555762C2778760513 @default.
- W1517555762 hasConceptScore W1517555762C2778979269 @default.
- W1517555762 hasConceptScore W1517555762C38485361 @default.
- W1517555762 hasConceptScore W1517555762C48349386 @default.
- W1517555762 hasConceptScore W1517555762C538909803 @default.
- W1517555762 hasConceptScore W1517555762C55493867 @default.
- W1517555762 hasConceptScore W1517555762C86803240 @default.
- W1517555762 hasConceptScore W1517555762C98274493 @default.
- W1517555762 hasFunder F4320334884 @default.
- W1517555762 hasIssue "S1" @default.
- W1517555762 hasLocation W15175557621 @default.
- W1517555762 hasOpenAccess W1517555762 @default.
- W1517555762 hasPrimaryLocation W15175557621 @default.
- W1517555762 hasRelatedWork W1590009324 @default.
- W1517555762 hasRelatedWork W164681620 @default.
- W1517555762 hasRelatedWork W1969555927 @default.
- W1517555762 hasRelatedWork W1993548188 @default.
- W1517555762 hasRelatedWork W2213996271 @default.
- W1517555762 hasRelatedWork W2415799310 @default.
- W1517555762 hasRelatedWork W2766233192 @default.
- W1517555762 hasRelatedWork W2891721693 @default.
- W1517555762 hasRelatedWork W3200659209 @default.
- W1517555762 hasRelatedWork W3214998341 @default.
- W1517555762 hasVolume "29" @default.
- W1517555762 isParatext "false" @default.
- W1517555762 isRetracted "false" @default.
- W1517555762 magId "1517555762" @default.
- W1517555762 workType "article" @default.