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- W1517839071 abstract "When rabbits were immunized with herpes virus, the production of early complement-requiring neutralizing antibody was followed by the appearance of neutralizing antibodies with a lower requirement for complement, which could be detected either by testing in the presence of lower concentrations of complement or by a prolonged incubation at 37° of virus-serum mixtures in the absence of complement. Kinetic experiments revealed that the virus-neutralizing velocity varied among sera of different immune stages when an equivalent concentration of antibody was tested, and that this velocity changed depending upon the amount of complement added, although the addition of complement did not influence the level of the persistent fraction. Neutralizing antibody in the γ-globulin fraction of an early serum and that of a hyperimmune serum both showed the properties characteristic for 7 S antibody, although a clear difference was seen in the requirement for complement." @default.
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- W1517839071 date "1965-05-01" @default.
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- W1517839071 title "Studies on the neutralization of herpes simplex virus" @default.
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- W1517839071 doi "https://doi.org/10.1016/0042-6822(65)90024-3" @default.
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