Matches in SemOpenAlex for { <https://semopenalex.org/work/W1518106648> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W1518106648 endingPage "4142" @default.
- W1518106648 startingPage "4138" @default.
- W1518106648 abstract "Abstract Two 36-amino acid-containing peptides (α1-CB2), isolated from rat skin and tendon collagen by cleavage of the α1 chain with CNBr, were subjected to enzymatic hydroxylation with collagen proline hydroxylase. The peptides differed initially only in that the ratio of hydroxyproline to proline was considerably lower in the tendon peptide, although the imino acid content of the two peptides was the same. In vitro hydroxylation produced a 75% increase in the hydroxyproline content of the tendon peptide but only an 8% increase in hydroxyproline in the skin peptide. These findings provide direct confirmation of the suggestion, made in an earlier study, that intracellular factors other than the sequences of collagen chains in skin and tendon account for the differences in the degree of hydroxylation of susceptible prolyl residues. Intact collagen preparations from various sources were similarly shown to be underhydroxylated. The distribution of newly formed hydroxyproline in α1-CB2 was investigated by analysis of chymotryptic fragments. Hydroxylation was largely limited to one of these fragments as predicted if hydroxylation occurred only at position 3 of the collagen triplet Gly-X-Y, i.e. at prolyl residues followed by glycine. This finding is in agreement with sequence analyses of vertebrate collagens and with enzymatic studies using synthetic peptides." @default.
- W1518106648 created "2016-06-24" @default.
- W1518106648 creator A5040441436 @default.
- W1518106648 creator A5041446287 @default.
- W1518106648 creator A5043009176 @default.
- W1518106648 date "1971-07-01" @default.
- W1518106648 modified "2023-10-17" @default.
- W1518106648 title "In Vitro Enzymatic Hydroxylation of Prolyl Residues in the α1-CB2 Fragment of Rat Collagen" @default.
- W1518106648 cites W1481257192 @default.
- W1518106648 cites W1486867504 @default.
- W1518106648 cites W1662521859 @default.
- W1518106648 cites W1965913915 @default.
- W1518106648 cites W1968657172 @default.
- W1518106648 cites W1975871680 @default.
- W1518106648 cites W1994089385 @default.
- W1518106648 cites W1994955127 @default.
- W1518106648 cites W2001450136 @default.
- W1518106648 cites W2005773196 @default.
- W1518106648 cites W2032004740 @default.
- W1518106648 cites W2036137358 @default.
- W1518106648 cites W2046163459 @default.
- W1518106648 cites W2050005762 @default.
- W1518106648 cites W2051299874 @default.
- W1518106648 cites W2055830465 @default.
- W1518106648 cites W2056970775 @default.
- W1518106648 cites W2058278497 @default.
- W1518106648 cites W2070195347 @default.
- W1518106648 cites W2075750953 @default.
- W1518106648 cites W2086438229 @default.
- W1518106648 cites W2086439654 @default.
- W1518106648 cites W2146350165 @default.
- W1518106648 cites W2196224599 @default.
- W1518106648 cites W2470398077 @default.
- W1518106648 doi "https://doi.org/10.1016/s0021-9258(18)62064-2" @default.
- W1518106648 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5090038" @default.
- W1518106648 hasPublicationYear "1971" @default.
- W1518106648 type Work @default.
- W1518106648 sameAs 1518106648 @default.
- W1518106648 citedByCount "22" @default.
- W1518106648 crossrefType "journal-article" @default.
- W1518106648 hasAuthorship W1518106648A5040441436 @default.
- W1518106648 hasAuthorship W1518106648A5041446287 @default.
- W1518106648 hasAuthorship W1518106648A5043009176 @default.
- W1518106648 hasBestOaLocation W15181066481 @default.
- W1518106648 hasConcept C181199279 @default.
- W1518106648 hasConcept C185592680 @default.
- W1518106648 hasConcept C199360897 @default.
- W1518106648 hasConcept C202751555 @default.
- W1518106648 hasConcept C2776235265 @default.
- W1518106648 hasConcept C2781109383 @default.
- W1518106648 hasConcept C41008148 @default.
- W1518106648 hasConcept C55493867 @default.
- W1518106648 hasConcept C71240020 @default.
- W1518106648 hasConceptScore W1518106648C181199279 @default.
- W1518106648 hasConceptScore W1518106648C185592680 @default.
- W1518106648 hasConceptScore W1518106648C199360897 @default.
- W1518106648 hasConceptScore W1518106648C202751555 @default.
- W1518106648 hasConceptScore W1518106648C2776235265 @default.
- W1518106648 hasConceptScore W1518106648C2781109383 @default.
- W1518106648 hasConceptScore W1518106648C41008148 @default.
- W1518106648 hasConceptScore W1518106648C55493867 @default.
- W1518106648 hasConceptScore W1518106648C71240020 @default.
- W1518106648 hasIssue "13" @default.
- W1518106648 hasLocation W15181066481 @default.
- W1518106648 hasOpenAccess W1518106648 @default.
- W1518106648 hasPrimaryLocation W15181066481 @default.
- W1518106648 hasRelatedWork W1603677234 @default.
- W1518106648 hasRelatedWork W1973480752 @default.
- W1518106648 hasRelatedWork W1999282026 @default.
- W1518106648 hasRelatedWork W2217679042 @default.
- W1518106648 hasRelatedWork W2370045143 @default.
- W1518106648 hasRelatedWork W2525971763 @default.
- W1518106648 hasRelatedWork W2593147304 @default.
- W1518106648 hasRelatedWork W3132641048 @default.
- W1518106648 hasRelatedWork W4225394062 @default.
- W1518106648 hasRelatedWork W4253208712 @default.
- W1518106648 hasVolume "246" @default.
- W1518106648 isParatext "false" @default.
- W1518106648 isRetracted "false" @default.
- W1518106648 magId "1518106648" @default.
- W1518106648 workType "article" @default.