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- W1518131211 abstract "Publisher Summary The first synthesis of carbohydrate-derived cyclic enol ethers (glycals) was developed by Emil Fischer early in the 20th century, featuring reductive elimination of glycosyl halides from carbohydrate starting materials. A newer approach to glycals features ring-closing metathesis of vinyl ethers with terminal alkenes. The development of methods for glycal synthesis has been accompanied by studies on the regio- and stereoselective functionalization of glycals, which can be applied to the introduction of functional groups at the 2-position. Thus, an endo-regioselective “alkynol cycloisomerization” process would provide another pathway to the synthesis of various cyclic enol ethers, including possibly glycals, if a reaction that is compatible with a variety of functional groups can be developed. With the discovery of six-membered ring formation via tungsten carbonyl reagents, the possibilities of synthesizing not only hexose sugars but also glycosides were considered. To test for the compatibility of alkynes with glycoside-forming methodologies, a microscale experiment with iodoglycosylation of chiral non-racemic alkynyl alcohol with commercially available tri-O-acetyl-D-glucal (25) has been conducted. The product iodoglycoside was observed as a single diastereomer by 1H-nuclear magnetic resonance (NMR) analysis of the reaction mixture." @default.
- W1518131211 created "2016-06-24" @default.
- W1518131211 creator A5075033189 @default.
- W1518131211 date "2004-01-01" @default.
- W1518131211 modified "2023-09-23" @default.
- W1518131211 title "Chapter 12 The invention of the alkynol cycloisomerization reaction: Application to the synthesis of digitoxin" @default.
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- W1518131211 cites W2021427228 @default.
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- W1518131211 cites W2028889433 @default.
- W1518131211 cites W2030171791 @default.
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- W1518131211 cites W2037172987 @default.
- W1518131211 cites W2037668530 @default.
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- W1518131211 doi "https://doi.org/10.1016/s1874-6004(04)80035-2" @default.
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