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• W15183712 abstract "No AccessJournal of Urology1 Dec 1989Radical Radiotherapy for Muscle Invasive Transitional Cell Carcinoma of the Bladder: Failure Analysis Mary K. Gospodarowicz, N.V. Hawkins, G.A. Rawlings, J.G. Connolly, M.A.S. Jewett, G.M. Thomas, J.G. Herman, P.G. Garrett, T. Chua, W. Duncan, M. Buckspan, L. Sugar, and W.D. Rider Mary K. GospodarowiczMary K. Gospodarowicz More articles by this author , N.V. HawkinsN.V. Hawkins More articles by this author , G.A. RawlingsG.A. Rawlings More articles by this author , J.G. ConnollyJ.G. Connolly More articles by this author , M.A.S. JewettM.A.S. Jewett More articles by this author , G.M. ThomasG.M. Thomas More articles by this author , J.G. HermanJ.G. Herman More articles by this author , P.G. GarrettP.G. Garrett More articles by this author , T. ChuaT. Chua More articles by this author , W. DuncanW. Duncan More articles by this author , M. BuckspanM. Buckspan More articles by this author , L. SugarL. Sugar More articles by this author , and W.D. RiderW.D. Rider More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)39122-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Patients with muscle invasive carcinoma of the bladder treated with radical radiation were prospectively documented and followed in an attempt to identify prognostic factors predictive of the response to treatment. Data on 121 consecutive patients treated with radical radiation between 1981 and 1985 are presented. Over-all actuarial survival of the patient population (median age 70 years) was 31.6% at 5 years and cause-specific survival was 44.8%. At analysis 33 of 121 patients (27.3%) were alive with preserved bladder function. Independent prognostic factors for cause-specific survival and for complete response with radical radiation were tumor configuration, hemoglobin level and clinical stage. The rate free of local relapse was significantly influenced by stage and presence of coexistent carcinoma in situ. The study suggests that factors other than stage and grade influence prognosis in invasive bladder cancer and should be considered in interpreting treatment results. © 1989 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byGriebling T (2013) Re: Evaluation of Acute Toxicity and Symptoms Palliation in a Hypofractionated Weekly Schedule of External Radiotherapy for Elderly Patients with Muscular Invasive Bladder CancerJournal of Urology, VOL. 190, NO. 3, (865-866), Online publication date: 1-Sep-2013.COLQUHOUN A, JONES G, MONEEF M, BOWMAN K, KOCKELBERGH R, SYMONDS R, STEWARD W and MELLON J (2018) Improving and Predicting Radiosensitivity in Muscle Invasive Bladder CancerJournal of Urology, VOL. 169, NO. 6, (1983-1992), Online publication date: 1-Jun-2003.KIM H and STEINBERG G (2018) THE CURRENT STATUS OF BLADDER PRESERVATION IN THE TREATMENT OF MUSCLE INVASIVE BLADDER CANCERJournal of Urology, VOL. 164, NO. 3 Part 1, (627-632), Online publication date: 1-Sep-2000.SHIPLEY W, KAUFMAN D, HENEY N, ALTHAUSEN A and ZIETMAN A (2018) AN UPDATE OF COMBINED MODALITY THERAPY FOR PATIENTS WITH MUSCLE INVADING BLADDER CANCER USING SELECTIVE BLADDER PRESERVATION OR CYSTECTOMYJournal of Urology, VOL. 162, NO. 2, (445-450), Online publication date: 1-Aug-1999.ZIETMAN A, SHIPLEY W, KAUFMAN D, ZEHR E, HENEY N, ALTHAUSEN A and McGOVERN F (2018) A PHASE I/II TRIAL OF TRANSURETHRAL SURGERY COMBINED WITH CONCURRENT CISPLATIN, 5-FLUOROURACIL AND TWICE DAILY RADIATION FOLLOWED BY SELECTIVE BLADDER PRESERVATION IN OPERABLE PATIENTS WITH MUSCLE INVADING BLADDER CANCERJournal of Urology, VOL. 160, NO. 5, (1673-1677), Online publication date: 1-Nov-1998.Chauvet B, Brewer Y, Felix-Faure C, Davin J, Choquenet C and Reboul F (2018) Concurrent Cisplatin and Radiotherapy for Patients with Muscle Invasive Bladder Cancer Who are not Candidates for Radical CystectomyJournal of Urology, VOL. 156, NO. 4, (1258-1262), Online publication date: 1-Oct-1996.Donat S, Herr H, Bajorin D, Fair W, Sogani P, Russo P, Sheinfeld J and Scher H (2018) Methotrexate, Vinblastine, Doxorubicin and Cisplatin Chemotherapy and Cystectomy for Unresectable Bladder CancerJournal of Urology, VOL. 156, NO. 2, (368-371), Online publication date: 1-Aug-1996.Sengelov L, Kamby C and von der Maase H (2018) Pattern of Metastases in Relation to Characteristics of Primary Tumor and Treatment in Patients with Disseminated Urothelial CarcinomaJournal of Urology, VOL. 155, NO. 1, (111-114), Online publication date: 1-Jan-1996.Thrasher J and Crawford E (2018) Current Management of Invasive and Metastatic Transitional Cell Carcinoma of the BladderJournal of Urology, VOL. 149, NO. 5 Part 1, (957-972), Online publication date: 1-May-1993.Vogelzang N, Moormeier J, Awan A, Weichselbaum R, Farah R, Straus F, Schoenberg H and Chodak G (2018) Methotrexate, Vinblastine, Doxorubicin and Cisplatin followed by Radiotherapy or Surgery for Muscle Invasive Bladder Cancer: The University of Chicago ExperienceJournal of Urology, VOL. 149, NO. 4, (753-757), Online publication date: 1-Apr-1993. Volume 142Issue 6December 1989Page: 1448-1453 Advertisement Copyright & Permissions© 1989 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Mary K. Gospodarowicz More articles by this author N.V. Hawkins More articles by this author G.A. Rawlings More articles by this author J.G. Connolly More articles by this author M.A.S. Jewett More articles by this author G.M. Thomas More articles by this author J.G. Herman More articles by this author P.G. Garrett More articles by this author T. Chua More articles by this author W. Duncan More articles by this author M. Buckspan More articles by this author L. Sugar More articles by this author W.D. Rider More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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