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- W151876204 startingPage "995" @default.
- W151876204 abstract "Apolipoprotein D (apo D), a lipocalin transporter of small hydrophobic molecules could play an important role in several neurodegenerative diseases. However, its role in those diseases remains unclear. There has been reported increments of apo D in relation with different neuropathologic diseases. Recently, we reported the absence of apo D in neurons of substantia nigra which can contribute to the lability of neurons to oxidative damage. In order to determine the relationship between apo D expression and neuronal death, we studied the expression of apo D in various regions of human brains from patients without any neurological or psychological disorders, in relation with the neuronal damage revealed by Fluoro-Jade B staining. The absence of expression for apo D in injured neurons and the negative staining for Fluoro-Jade B of neurons that express apo D was observed in all sections studied. These findings are in accordance with the role possibly played by apo D in the neuroprotection of the nervous system" @default.
- W151876204 created "2016-06-24" @default.
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- W151876204 date "2008-08-01" @default.
- W151876204 modified "2023-09-24" @default.
- W151876204 title "Apolipoprotein D expression absence in degenerating neurons of human central nervous system." @default.
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- W151876204 doi "https://doi.org/10.14670/hh-23.995" @default.
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