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- W1519202038 abstract "This chapter attempts to define the anatomical organization of the prefrontal cortex (OMPFC) in macaque monkeys, including its architectonic structure and intrinsic and extrinsic connections, in hopes that this will enable more complete analysis of its function. Lesions of the OMPFC, such as reported in the classical case of Phineas Gage and in similar contemporary cases, have been reported to produce disturbances in emotional reactions to sensory stimuli, and disruption of social conduct so severe that they constitute a radical change in personality. Although the basis for this deficit remains unclear, it has been suggested that it is related to disconnection of pathways between the cortex and autonomic systems that govern visceral responses normally associated with affective stimuli. The results indicate that the OMPFC, like other cortical regions, is composed of a number of relatively discrete cortical areas. Each of these areas has distinct structure and connections, and presumably plays a distinct functional role within the overall function of the region." @default.
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- W1519202038 title "Chapter 31 Networks related to the orbital and medial prefrontal cortex; a substrate for emotional behavior?" @default.
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- W1519202038 doi "https://doi.org/10.1016/s0079-6123(08)61885-3" @default.
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