Matches in SemOpenAlex for { <https://semopenalex.org/work/W1519241567> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1519241567 endingPage "3551" @default.
- W1519241567 startingPage "3542" @default.
- W1519241567 abstract "In the previous 2 papers, we focused on the selective affinities that growth cones display for specific axonal pathways. Little is known, however, about how this orthogonal scaffold of axonal pathways in the CNS is established in the first place, and what, if any, role glia might play in these events. Here we show an important relationship between pioneering growth cones and primitive glial cells in the developing longitudinal connectives and peripheral nerve roots of the grasshopper embryo. We describe a preformed glial pathway for the formation of the intersegmental nerve, one of the major roots exiting the CNS. The growth cones that pioneer this nerve display a selective affinity for the segment boundary cell (SBC), a primitive glial cell that establishes the location of this nerve root. Similar glial cells are also found along the pathway where the longitudinal connectives form, and they too may play an important role in the formation of the first longitudinal axonal pathways. Experimental analysis shows that when the SBC is ablated, the growth cones that normally turn laterally to pioneer the intersegmental nerve do not do so, thus confirming the importance of the guiding role of this glial cell. We postulate that a simple orthogonal scaffold of primitive glia is involved in the initial patterning of axonal pathways within and exiting the insect CNS; this concept is remarkably similar to the blueprint hypothesis proposed by Singer et al. (1979) to explain the development of axon pathways in vertebrates." @default.
- W1519241567 created "2016-06-24" @default.
- W1519241567 creator A5065759294 @default.
- W1519241567 creator A5072799614 @default.
- W1519241567 date "1986-12-01" @default.
- W1519241567 modified "2023-10-09" @default.
- W1519241567 title "Guidance of neuronal growth cones in the grasshopper embryo. III. Recognition of specific glial pathways" @default.
- W1519241567 cites W1521905577 @default.
- W1519241567 cites W1550765434 @default.
- W1519241567 cites W1567004279 @default.
- W1519241567 cites W1593703656 @default.
- W1519241567 cites W1640978204 @default.
- W1519241567 cites W1707249081 @default.
- W1519241567 cites W1867402052 @default.
- W1519241567 cites W1964936262 @default.
- W1519241567 cites W1972434605 @default.
- W1519241567 cites W1979814500 @default.
- W1519241567 cites W1981091775 @default.
- W1519241567 cites W1981147697 @default.
- W1519241567 cites W1986124023 @default.
- W1519241567 cites W1996133944 @default.
- W1519241567 cites W1998837883 @default.
- W1519241567 cites W2006939821 @default.
- W1519241567 cites W2013293997 @default.
- W1519241567 cites W2013968703 @default.
- W1519241567 cites W2044344777 @default.
- W1519241567 cites W2053623203 @default.
- W1519241567 cites W2053671252 @default.
- W1519241567 cites W2066465855 @default.
- W1519241567 cites W2075126673 @default.
- W1519241567 cites W2185253868 @default.
- W1519241567 cites W350219671 @default.
- W1519241567 doi "https://doi.org/10.1523/jneurosci.06-12-03542.1986" @default.
- W1519241567 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6568670" @default.
- W1519241567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3794788" @default.
- W1519241567 hasPublicationYear "1986" @default.
- W1519241567 type Work @default.
- W1519241567 sameAs 1519241567 @default.
- W1519241567 citedByCount "157" @default.
- W1519241567 countsByYear W15192415672012 @default.
- W1519241567 countsByYear W15192415672013 @default.
- W1519241567 countsByYear W15192415672014 @default.
- W1519241567 countsByYear W15192415672015 @default.
- W1519241567 countsByYear W15192415672016 @default.
- W1519241567 countsByYear W15192415672018 @default.
- W1519241567 countsByYear W15192415672020 @default.
- W1519241567 crossrefType "journal-article" @default.
- W1519241567 hasAuthorship W1519241567A5065759294 @default.
- W1519241567 hasAuthorship W1519241567A5072799614 @default.
- W1519241567 hasBestOaLocation W15192415671 @default.
- W1519241567 hasConcept C105702510 @default.
- W1519241567 hasConcept C132538176 @default.
- W1519241567 hasConcept C135903288 @default.
- W1519241567 hasConcept C169760540 @default.
- W1519241567 hasConcept C170493617 @default.
- W1519241567 hasConcept C2777542381 @default.
- W1519241567 hasConcept C2777594495 @default.
- W1519241567 hasConcept C2779530196 @default.
- W1519241567 hasConcept C529278444 @default.
- W1519241567 hasConcept C54355233 @default.
- W1519241567 hasConcept C69125201 @default.
- W1519241567 hasConcept C86803240 @default.
- W1519241567 hasConcept C95444343 @default.
- W1519241567 hasConceptScore W1519241567C105702510 @default.
- W1519241567 hasConceptScore W1519241567C132538176 @default.
- W1519241567 hasConceptScore W1519241567C135903288 @default.
- W1519241567 hasConceptScore W1519241567C169760540 @default.
- W1519241567 hasConceptScore W1519241567C170493617 @default.
- W1519241567 hasConceptScore W1519241567C2777542381 @default.
- W1519241567 hasConceptScore W1519241567C2777594495 @default.
- W1519241567 hasConceptScore W1519241567C2779530196 @default.
- W1519241567 hasConceptScore W1519241567C529278444 @default.
- W1519241567 hasConceptScore W1519241567C54355233 @default.
- W1519241567 hasConceptScore W1519241567C69125201 @default.
- W1519241567 hasConceptScore W1519241567C86803240 @default.
- W1519241567 hasConceptScore W1519241567C95444343 @default.
- W1519241567 hasIssue "12" @default.
- W1519241567 hasLocation W15192415671 @default.
- W1519241567 hasLocation W15192415672 @default.
- W1519241567 hasLocation W15192415673 @default.
- W1519241567 hasLocation W15192415674 @default.
- W1519241567 hasOpenAccess W1519241567 @default.
- W1519241567 hasPrimaryLocation W15192415671 @default.
- W1519241567 hasRelatedWork W1540458273 @default.
- W1519241567 hasRelatedWork W2030150951 @default.
- W1519241567 hasRelatedWork W2098827723 @default.
- W1519241567 hasRelatedWork W2100976322 @default.
- W1519241567 hasRelatedWork W2102147520 @default.
- W1519241567 hasRelatedWork W2140239268 @default.
- W1519241567 hasRelatedWork W2143767826 @default.
- W1519241567 hasRelatedWork W2147701184 @default.
- W1519241567 hasRelatedWork W2545010473 @default.
- W1519241567 hasRelatedWork W4211072527 @default.
- W1519241567 hasVolume "6" @default.
- W1519241567 isParatext "false" @default.
- W1519241567 isRetracted "false" @default.
- W1519241567 magId "1519241567" @default.
- W1519241567 workType "article" @default.