FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1519260014> ?p ?o ?g. }

• W1519260014 endingPage "23324" @default.
• W1519260014 startingPage "23318" @default.
• W1519260014 abstract "Protein-tyrosine phosphorylation plays a critical role in the high-affinity IgE receptor (Fc epsilon RI) signaling. Here we investigated the involvement of the tyrosine kinase p72syk in Fc epsilon RI signaling in the rat mast cell line RBL-2H3. Specific antibodies were raised against peptides synthesized on the basis of the deduced peptide sequence of an essentially full-length rat syk cDNA. The expression of p72syk in RBL-2H3 cells was demonstrated with these antibodies. The aggregation of Fc epsilon RI led to the tyrosine phosphorylation of p72syk that was detected after 15 s of stimulation, reached a plateau by 5 min, and was not induced by calcium influx or protein kinase C activation. Association of p72syk with the tyrosine phosphorylated Fc epsilon RI gamma chain was detected only after receptor aggregation. We previously demonstrated that aggregation of the Fc epsilon RI on mast cells results in the tyrosine phosphorylation of a 72-kDa protein (pp72) involved in IgE signaling. The depletion of p72syk from RBL-2H3 cell lysates resulted in only a slight decrease in the amount of pp72. These results demonstrate that pp72 is composed of several phosphoproteins and identify p72syk as one component of pp72. These data, together with recent observations in T cells, indicate that the interaction between p72syk-related tyrosine kinases and zeta-related proteins could play an important role in signal transduction." @default.
• W1519260014 created "2016-06-24" @default.
• W1519260014 creator A5028487381 @default.
• W1519260014 creator A5030964840 @default.
• W1519260014 creator A5056343746 @default.
• W1519260014 creator A5074163203 @default.
• W1519260014 creator A5083238922 @default.
• W1519260014 date "1993-11-01" @default.
• W1519260014 modified "2023-10-01" @default.
• W1519260014 title "Protein-tyrosine kinase p72syk in high affinity IgE receptor signaling. Identification as a component of pp72 and association with the receptor gamma chain after receptor aggregation." @default.
• W1519260014 cites W1481543280 @default.
• W1519260014 cites W1481629090 @default.
• W1519260014 cites W1482211797 @default.
• W1519260014 cites W1492670710 @default.
• W1519260014 cites W1525901333 @default.
• W1519260014 cites W1527505565 @default.
• W1519260014 cites W1528493806 @default.
• W1519260014 cites W1542743692 @default.
• W1519260014 cites W1543778012 @default.
• W1519260014 cites W1557763992 @default.
• W1519260014 cites W1567044759 @default.
• W1519260014 cites W1704017123 @default.
• W1519260014 cites W1968585354 @default.
• W1519260014 cites W1985428786 @default.
• W1519260014 cites W1986549185 @default.
• W1519260014 cites W1997634231 @default.
• W1519260014 cites W2009597900 @default.
• W1519260014 cites W2036306165 @default.
• W1519260014 cites W2037030067 @default.
• W1519260014 cites W2044791151 @default.
• W1519260014 cites W2052561585 @default.
• W1519260014 cites W2056030264 @default.
• W1519260014 cites W2070431736 @default.
• W1519260014 cites W2071984343 @default.
• W1519260014 cites W2074680623 @default.
• W1519260014 cites W2089577767 @default.
• W1519260014 cites W2139494439 @default.
• W1519260014 cites W2141179251 @default.
• W1519260014 cites W2156639496 @default.
• W1519260014 cites W4249736906 @default.
• W1519260014 doi "https://doi.org/10.1016/s0021-9258(19)49465-9" @default.
• W1519260014 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7693687" @default.
• W1519260014 hasPublicationYear "1993" @default.
• W1519260014 type Work @default.
• W1519260014 sameAs 1519260014 @default.
• W1519260014 citedByCount "227" @default.
• W1519260014 countsByYear W15192600142012 @default.
• W1519260014 countsByYear W15192600142013 @default.
• W1519260014 countsByYear W15192600142014 @default.
• W1519260014 countsByYear W15192600142016 @default.
• W1519260014 countsByYear W15192600142019 @default.
• W1519260014 countsByYear W15192600142020 @default.
• W1519260014 countsByYear W15192600142021 @default.
• W1519260014 countsByYear W15192600142023 @default.
• W1519260014 crossrefType "journal-article" @default.
• W1519260014 hasAuthorship W1519260014A5028487381 @default.
• W1519260014 hasAuthorship W1519260014A5030964840 @default.
• W1519260014 hasAuthorship W1519260014A5056343746 @default.
• W1519260014 hasAuthorship W1519260014A5074163203 @default.
• W1519260014 hasAuthorship W1519260014A5083238922 @default.
• W1519260014 hasBestOaLocation W15192600141 @default.
• W1519260014 hasConcept C101544691 @default.
• W1519260014 hasConcept C153911025 @default.
• W1519260014 hasConcept C170493617 @default.
• W1519260014 hasConcept C180361614 @default.
• W1519260014 hasConcept C185592680 @default.
• W1519260014 hasConcept C23440912 @default.
• W1519260014 hasConcept C2775960820 @default.
• W1519260014 hasConcept C2911166042 @default.
• W1519260014 hasConcept C42362537 @default.
• W1519260014 hasConcept C55493867 @default.
• W1519260014 hasConcept C79186569 @default.
• W1519260014 hasConcept C86803240 @default.
• W1519260014 hasConceptScore W1519260014C101544691 @default.
• W1519260014 hasConceptScore W1519260014C153911025 @default.
• W1519260014 hasConceptScore W1519260014C170493617 @default.
• W1519260014 hasConceptScore W1519260014C180361614 @default.
• W1519260014 hasConceptScore W1519260014C185592680 @default.
• W1519260014 hasConceptScore W1519260014C23440912 @default.
• W1519260014 hasConceptScore W1519260014C2775960820 @default.
• W1519260014 hasConceptScore W1519260014C2911166042 @default.
• W1519260014 hasConceptScore W1519260014C42362537 @default.
• W1519260014 hasConceptScore W1519260014C55493867 @default.
• W1519260014 hasConceptScore W1519260014C79186569 @default.
• W1519260014 hasConceptScore W1519260014C86803240 @default.
• W1519260014 hasIssue "31" @default.
• W1519260014 hasLocation W15192600141 @default.
• W1519260014 hasOpenAccess W1519260014 @default.
• W1519260014 hasPrimaryLocation W15192600141 @default.
• W1519260014 hasRelatedWork W1497755692 @default.
• W1519260014 hasRelatedWork W168358005 @default.
• W1519260014 hasRelatedWork W1969206533 @default.
• W1519260014 hasRelatedWork W1977179627 @default.
• W1519260014 hasRelatedWork W1991624054 @default.
• W1519260014 hasRelatedWork W2108936238 @default.
• W1519260014 hasRelatedWork W2395338823 @default.
• W1519260014 hasRelatedWork W2397963469 @default.
• W1519260014 hasRelatedWork W2798324004 @default.

• next