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- W1519299809 abstract "Due to their numerous applications, fluorinated amino acids have recently attracted significant attention. The preparation of fluorine-containing phenylalanines, heteroaryl alanines and aliphatic fluorinated amino acids using Mitsunobu–Tsunoda alkylation of a chiral nucleophilic glycine equivalent with readily available alcohol substrates is described. The reaction proceeds in high yields and with excellent diastereoselectivity. This method provides an efficient synthetic route to fluorinated amino acids for which asymmetric approaches are scarce." @default.
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- W1519299809 date "2014-01-14" @default.
- W1519299809 modified "2023-09-24" @default.
- W1519299809 title "A Convenient Method for the Asymmetric Synthesis of Fluorinated α-Amino Acids from Alcohols" @default.
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- W1519299809 doi "https://doi.org/10.1002/ejoc.201301718" @default.
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