Matches in SemOpenAlex for { <https://semopenalex.org/work/W1519333228> ?p ?o ?g. }
- W1519333228 endingPage "458" @default.
- W1519333228 startingPage "449" @default.
- W1519333228 abstract "A survey of purine anabolic and catabolic enzymes has resulted in identification of major pathways in schistosome nucleotide biosynthesis. It is shown that multiple pathways for the incorporation of purine bases and nucleosides exist. The evidence suggests that adenosine phosphoribosyltransferase (APRT) activity is about ten times greater than adenosine kinase activity. Furthermore adenosine is converted to AMP principally via the pathway of adenosine deaminase, followed by conversion of inosine to hypoxanthine. In this sequence hypoxanthine phosphoribosyltransferase (HPRT) activity is rate limiting. On the basis of enzyme activities determined, one can suggest candidates of nucleotide analogs which might be useful chemotherapeutic agents." @default.
- W1519333228 created "2016-06-24" @default.
- W1519333228 creator A5000189544 @default.
- W1519333228 creator A5003969080 @default.
- W1519333228 creator A5035744333 @default.
- W1519333228 creator A5057864747 @default.
- W1519333228 creator A5061700859 @default.
- W1519333228 creator A5078821665 @default.
- W1519333228 date "1973-02-01" @default.
- W1519333228 modified "2023-09-27" @default.
- W1519333228 title "Pathways of nucleotide metabolism in Schistosoma mansoni—III" @default.
- W1519333228 cites W1490801680 @default.
- W1519333228 cites W1561017210 @default.
- W1519333228 cites W1572431390 @default.
- W1519333228 cites W1596965006 @default.
- W1519333228 cites W1597365737 @default.
- W1519333228 cites W1597471785 @default.
- W1519333228 cites W1669190037 @default.
- W1519333228 cites W1966695426 @default.
- W1519333228 cites W2015212707 @default.
- W1519333228 cites W2040376024 @default.
- W1519333228 cites W2068158422 @default.
- W1519333228 cites W2320298147 @default.
- W1519333228 cites W2440553874 @default.
- W1519333228 cites W4240261036 @default.
- W1519333228 cites W84093949 @default.
- W1519333228 doi "https://doi.org/10.1016/0006-2952(73)90286-4" @default.
- W1519333228 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4691874" @default.
- W1519333228 hasPublicationYear "1973" @default.
- W1519333228 type Work @default.
- W1519333228 sameAs 1519333228 @default.
- W1519333228 citedByCount "40" @default.
- W1519333228 countsByYear W15193332282012 @default.
- W1519333228 countsByYear W15193332282013 @default.
- W1519333228 countsByYear W15193332282014 @default.
- W1519333228 countsByYear W15193332282016 @default.
- W1519333228 countsByYear W15193332282017 @default.
- W1519333228 countsByYear W15193332282018 @default.
- W1519333228 countsByYear W15193332282019 @default.
- W1519333228 countsByYear W15193332282023 @default.
- W1519333228 crossrefType "journal-article" @default.
- W1519333228 hasAuthorship W1519333228A5000189544 @default.
- W1519333228 hasAuthorship W1519333228A5003969080 @default.
- W1519333228 hasAuthorship W1519333228A5035744333 @default.
- W1519333228 hasAuthorship W1519333228A5057864747 @default.
- W1519333228 hasAuthorship W1519333228A5061700859 @default.
- W1519333228 hasAuthorship W1519333228A5078821665 @default.
- W1519333228 hasConcept C104317684 @default.
- W1519333228 hasConcept C143065580 @default.
- W1519333228 hasConcept C169586020 @default.
- W1519333228 hasConcept C181199279 @default.
- W1519333228 hasConcept C185592680 @default.
- W1519333228 hasConcept C2776476023 @default.
- W1519333228 hasConcept C2776991684 @default.
- W1519333228 hasConcept C2777610669 @default.
- W1519333228 hasConcept C2780876210 @default.
- W1519333228 hasConcept C2781116151 @default.
- W1519333228 hasConcept C2909697302 @default.
- W1519333228 hasConcept C34628245 @default.
- W1519333228 hasConcept C40507961 @default.
- W1519333228 hasConcept C512185932 @default.
- W1519333228 hasConcept C55493867 @default.
- W1519333228 hasConcept C78179603 @default.
- W1519333228 hasConcept C86803240 @default.
- W1519333228 hasConcept C96942376 @default.
- W1519333228 hasConceptScore W1519333228C104317684 @default.
- W1519333228 hasConceptScore W1519333228C143065580 @default.
- W1519333228 hasConceptScore W1519333228C169586020 @default.
- W1519333228 hasConceptScore W1519333228C181199279 @default.
- W1519333228 hasConceptScore W1519333228C185592680 @default.
- W1519333228 hasConceptScore W1519333228C2776476023 @default.
- W1519333228 hasConceptScore W1519333228C2776991684 @default.
- W1519333228 hasConceptScore W1519333228C2777610669 @default.
- W1519333228 hasConceptScore W1519333228C2780876210 @default.
- W1519333228 hasConceptScore W1519333228C2781116151 @default.
- W1519333228 hasConceptScore W1519333228C2909697302 @default.
- W1519333228 hasConceptScore W1519333228C34628245 @default.
- W1519333228 hasConceptScore W1519333228C40507961 @default.
- W1519333228 hasConceptScore W1519333228C512185932 @default.
- W1519333228 hasConceptScore W1519333228C55493867 @default.
- W1519333228 hasConceptScore W1519333228C78179603 @default.
- W1519333228 hasConceptScore W1519333228C86803240 @default.
- W1519333228 hasConceptScore W1519333228C96942376 @default.
- W1519333228 hasIssue "4" @default.
- W1519333228 hasLocation W15193332281 @default.
- W1519333228 hasLocation W15193332282 @default.
- W1519333228 hasOpenAccess W1519333228 @default.
- W1519333228 hasPrimaryLocation W15193332281 @default.
- W1519333228 hasRelatedWork W1519333228 @default.
- W1519333228 hasRelatedWork W1991758207 @default.
- W1519333228 hasRelatedWork W1994066860 @default.
- W1519333228 hasRelatedWork W2003777890 @default.
- W1519333228 hasRelatedWork W2013157260 @default.
- W1519333228 hasRelatedWork W2016119250 @default.
- W1519333228 hasRelatedWork W2072782647 @default.
- W1519333228 hasRelatedWork W2093300815 @default.
- W1519333228 hasRelatedWork W2159710370 @default.
- W1519333228 hasRelatedWork W3024810324 @default.