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- W1519459909 abstract "The oesophagus co-ordinates the transport of food and fluid from the mouth to the stomach. The oesophagogastric junction (OGJ) is a physiological barrier which reduces reflux of gastric contents. In harmony, these processes limit contact of the swallowed bolus, refluxed acid and other chemicals with oesophageal mucosa. Disruption of function can interrupt bolus delivery or induce gastro-oesophageal reflux. Symptoms produced may range in severity from heartburn and regurgitation to dysphagia and pain. In the absence of disease on endoscopy and failure to respond to empirical therapy, guidelines recommend manometry and ambulatory reflux testing. An important advance of the modern HRM-based classification is that it is hierarchical; the OGJ is considered first because pathology within the OGJ will influence oesophageal function." @default.
- W1519459909 created "2016-06-24" @default.
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- W1519459909 date "2014-06-27" @default.
- W1519459909 modified "2023-10-16" @default.
- W1519459909 title "Physiology and function of the oesophagus" @default.
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- W1519459909 doi "https://doi.org/10.1002/9781118872796.ch1.2" @default.
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