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- W1519552014 abstract "Surface Igs of eight different human established lymphoblastoid lines were investigated by means of a radioassay method and cytotoxicity testing. The number of surface Ig sites varied from 1.0 to 4.5 × 10 5 per Ig positive cell in different lymphoid lines. µ heavy (H) chain and κ light (L) chains were the predominant surface Ig antigens encountered in most but not all cases. A molar excess of L chains was observed in five out of eight lymphoid lines. Multiple factors contributed to the excess of L chains. In certain lines a L chain excess was also present in secreted and in cellular Ig favoring an interpretation of unbalanced oversynthesis of L chains. Two lines, however, had the L chain excess restricted to surface Ig. Experiments on two of the lines with L chain excess demonstrated that while most Ig positive cells had both L and H chain surface antigens, a minor proportion of cells had only L chains detectable on their surface." @default.
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- W1519552014 date "1974-08-01" @default.
- W1519552014 modified "2023-09-23" @default.
- W1519552014 title "Immunoglobulin expression of cells from human lymphoblastoid lines. I. Heavy and light chain antigens of the cell surface." @default.
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