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- W1519588352 abstract "The decrease in plasma pyruvate kinase activity after administration of various tocopherols to vitamin E-deficient rats provided the basis for a 3-point parallelslope assay for vitamin E activity. Based on 6 replicate assays, RRR-α-tocopheryl acetate (RRR-α-TA) was 141% as active as all-rac-α-tocopheryl acetate (all-rac-α-TA). This confirms many previous reports with other bioassays and is in agreement with the unit-weight relationships assigned by The National Formulary. 2-ambo-α-Tocopheryl acetate was 97% as active as all-rac-α-TA indicating that only the configuration of the 2-position on the chromanol ring is important in determining the biological activity of α-tocopherol. vitamin E curative myopathy bioassay RRR-α-tocopheryl acetate all-rac-α-tocopheryl acetate 2-ambo-α-tocopheryl acetate relative potency" @default.
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- W1519588352 date "1982-07-01" @default.
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- W1519588352 title "Biopotency of α-Tocopherols as Determined by Curative Myopathy Bioassay in the Rat" @default.
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- W1519588352 doi "https://doi.org/10.1093/jn/112.7.1437" @default.
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