Matches in SemOpenAlex for { <https://semopenalex.org/work/W1519958729> ?p ?o ?g. }
- W1519958729 endingPage "226" @default.
- W1519958729 startingPage "183" @default.
- W1519958729 abstract "Deregulation and elevated expression of members of the Myc family of bHLHZip transcription factors are observed in a high percentage of tumors. This close association with human cancers has led to a tremendous effort to define their biological and biochemical activities. Although Myc family proteins have the capacity to elicit a wide range of cell behaviors, their principal function appears to be to drive cells into the cell cycle and to keep them there. However, forced expression of Myc profoundly sensitizes normal cells to apoptosis. Therefore, tumor formation caused by deregulated Myc expression requires cooperating events that disrupt pathways that mediate apoptosis. Myc-dependent tumor formation may also be impeded by a set of related bHLHZip proteins with the demonstrated potential to act as Myc antagonists in cell culture experiments. In this review, we examine the complex activities of Myc family proteins and how their actions might be regulated in the context of a network of bHLHZip proteins." @default.
- W1519958729 created "2016-06-24" @default.
- W1519958729 creator A5001559616 @default.
- W1519958729 creator A5039133215 @default.
- W1519958729 date "2004-01-01" @default.
- W1519958729 modified "2023-10-13" @default.
- W1519958729 title "Functions of Myc:Max in the Control of Cell Proliferation and Tumorigenesis" @default.
- W1519958729 cites W128302075 @default.
- W1519958729 cites W137827881 @default.
- W1519958729 cites W1451979937 @default.
- W1519958729 cites W1493931678 @default.
- W1519958729 cites W1500013333 @default.
- W1519958729 cites W1502418486 @default.
- W1519958729 cites W1547509454 @default.
- W1519958729 cites W1547608553 @default.
- W1519958729 cites W1548932088 @default.
- W1519958729 cites W1549051606 @default.
- W1519958729 cites W1600943063 @default.
- W1519958729 cites W1603531409 @default.
- W1519958729 cites W1622668755 @default.
- W1519958729 cites W1761484484 @default.
- W1519958729 cites W1805917608 @default.
- W1519958729 cites W1887854518 @default.
- W1519958729 cites W1898299209 @default.
- W1519958729 cites W1957236851 @default.
- W1519958729 cites W1964318436 @default.
- W1519958729 cites W1964461072 @default.
- W1519958729 cites W1964742508 @default.
- W1519958729 cites W1965009601 @default.
- W1519958729 cites W1965137961 @default.
- W1519958729 cites W1965159397 @default.
- W1519958729 cites W1966683022 @default.
- W1519958729 cites W1966793715 @default.
- W1519958729 cites W1968075576 @default.
- W1519958729 cites W1968710429 @default.
- W1519958729 cites W1971645561 @default.
- W1519958729 cites W1971657539 @default.
- W1519958729 cites W1971819775 @default.
- W1519958729 cites W1971918636 @default.
- W1519958729 cites W1972780353 @default.
- W1519958729 cites W1974188350 @default.
- W1519958729 cites W1974521227 @default.
- W1519958729 cites W1975489321 @default.
- W1519958729 cites W1975737390 @default.
- W1519958729 cites W1975740413 @default.
- W1519958729 cites W1976088130 @default.
- W1519958729 cites W1976091561 @default.
- W1519958729 cites W1976874039 @default.
- W1519958729 cites W1976963325 @default.
- W1519958729 cites W1980110416 @default.
- W1519958729 cites W1982598635 @default.
- W1519958729 cites W1983926998 @default.
- W1519958729 cites W1984159955 @default.
- W1519958729 cites W1984164498 @default.
- W1519958729 cites W1984903030 @default.
- W1519958729 cites W1984948591 @default.
- W1519958729 cites W1985160565 @default.
- W1519958729 cites W1986820083 @default.
- W1519958729 cites W1989009382 @default.
- W1519958729 cites W1989461823 @default.
- W1519958729 cites W1992390807 @default.
- W1519958729 cites W1992836970 @default.
- W1519958729 cites W1994405096 @default.
- W1519958729 cites W1996938751 @default.
- W1519958729 cites W1996949194 @default.
- W1519958729 cites W2000002736 @default.
- W1519958729 cites W2000215626 @default.
- W1519958729 cites W2002761352 @default.
- W1519958729 cites W2003110930 @default.
- W1519958729 cites W2003327103 @default.
- W1519958729 cites W2004205790 @default.
- W1519958729 cites W2008550494 @default.
- W1519958729 cites W2008797552 @default.
- W1519958729 cites W2010697949 @default.
- W1519958729 cites W2012598468 @default.
- W1519958729 cites W2013330927 @default.
- W1519958729 cites W2013729196 @default.
- W1519958729 cites W2014624348 @default.
- W1519958729 cites W2014735524 @default.
- W1519958729 cites W2015815772 @default.
- W1519958729 cites W2016567695 @default.
- W1519958729 cites W2017256489 @default.
- W1519958729 cites W2017761226 @default.
- W1519958729 cites W2020126480 @default.
- W1519958729 cites W2021963526 @default.
- W1519958729 cites W2024831440 @default.
- W1519958729 cites W2025438239 @default.
- W1519958729 cites W2028859420 @default.
- W1519958729 cites W2029829614 @default.
- W1519958729 cites W2029927926 @default.
- W1519958729 cites W2030816211 @default.
- W1519958729 cites W2031848573 @default.
- W1519958729 cites W2034427054 @default.
- W1519958729 cites W2037872087 @default.
- W1519958729 cites W2040239915 @default.
- W1519958729 cites W2040289803 @default.
- W1519958729 cites W2040803520 @default.
- W1519958729 cites W2041030270 @default.