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- W1520233514 abstract "Single-stranded progeny DNA is not formed when host cells are infected at the restrictive temperature with a temperature-sensitive coat protein mutant of øX174. Once begun, the synthesis of single-stranded DNA is interrupted when an infected culture is shifted from the permissive to the restrictive temperature. The synthesis of double-stranded “replicative form” DNA is observed under restrictive conditions. Upon shifting an infected culture from restrictive to permissive conditions after 30 minutes of infection, single-stranded DNA synthesis starts almost immediately. In this instance, the initial single-stranded viral DNA is formed out of the pre-formed double-stranded replicative form DNA by degradation of the complementary strand. The attachment of coat protein to the viral strand and the release of the viral strand from the double-stranded precursor appear to take place simultaneously." @default.
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- W1520233514 date "1968-01-01" @default.
- W1520233514 modified "2023-10-18" @default.
- W1520233514 title "Process of infection with bacteriophage øX174" @default.
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- W1520233514 doi "https://doi.org/10.1016/s0022-2836(68)80016-6" @default.
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