Matches in SemOpenAlex for { <https://semopenalex.org/work/W1520290721> ?p ?o ?g. }
- W1520290721 endingPage "19" @default.
- W1520290721 startingPage "4" @default.
- W1520290721 abstract "Diabetic retinopathy (DR) is one of the most common microvascular complications of diabetes and remains a major cause of preventable blindness among adults at working age. DR involves an abnormal pathology of major retinal cells, including retinal pigment epithelium, microaneurysms, inter-retinal oedema, haemorrhage, exudates (hard exudates) and intraocular neovascularization. The biochemical mechanisms associated with hyperglycaemic-induced DR are through multifactorial processes. Peroxisome proliferator-activated receptor-γ (PPAR-γ) plays an important role in the pathogenesis of DR by inhibiting diabetes-induced retinal leukostasis and leakage. Despite DR causing eventual blindness, only a few visual or ophthalmic symptoms are observed until visual loss develops. Therefore, early medical interventions and prevention are the current management strategies. Laser photocoagulation therapy is the most common treatment. However, this therapy may cause retinal damage and scarring. Herbal and traditional natural medicines may provide an alternative to prevent or delay the progression of DR. This review provides an analysis of the therapeutic potential of herbal and traditional natural medicines or their active components for the slowdown of progression of DR and their possible mechanism through the PPAR-γ pathway." @default.
- W1520290721 created "2016-06-24" @default.
- W1520290721 creator A5042960453 @default.
- W1520290721 creator A5083099452 @default.
- W1520290721 creator A5084676022 @default.
- W1520290721 date "2011-12-06" @default.
- W1520290721 modified "2023-10-17" @default.
- W1520290721 title "Modulation of diabetic retinopathy pathophysiology by natural medicines through PPAR-γ-related pharmacology" @default.
- W1520290721 cites W127305701 @default.
- W1520290721 cites W1504008270 @default.
- W1520290721 cites W1562566978 @default.
- W1520290721 cites W1633340712 @default.
- W1520290721 cites W1796060835 @default.
- W1520290721 cites W187440223 @default.
- W1520290721 cites W1898328784 @default.
- W1520290721 cites W1944346123 @default.
- W1520290721 cites W1967119121 @default.
- W1520290721 cites W1968625953 @default.
- W1520290721 cites W1968879585 @default.
- W1520290721 cites W1969430743 @default.
- W1520290721 cites W1973436528 @default.
- W1520290721 cites W1977157713 @default.
- W1520290721 cites W1977554203 @default.
- W1520290721 cites W1977760393 @default.
- W1520290721 cites W1978701318 @default.
- W1520290721 cites W1978996756 @default.
- W1520290721 cites W1980053858 @default.
- W1520290721 cites W1981170718 @default.
- W1520290721 cites W1982841054 @default.
- W1520290721 cites W1984984255 @default.
- W1520290721 cites W1985750839 @default.
- W1520290721 cites W1986564239 @default.
- W1520290721 cites W1987672280 @default.
- W1520290721 cites W1988171492 @default.
- W1520290721 cites W1988293663 @default.
- W1520290721 cites W1990188579 @default.
- W1520290721 cites W1992135527 @default.
- W1520290721 cites W1994417329 @default.
- W1520290721 cites W1996279996 @default.
- W1520290721 cites W1997540398 @default.
- W1520290721 cites W1998102786 @default.
- W1520290721 cites W1998948336 @default.
- W1520290721 cites W1999371496 @default.
- W1520290721 cites W2000498893 @default.
- W1520290721 cites W2001325871 @default.
- W1520290721 cites W2002503549 @default.
- W1520290721 cites W2002918909 @default.
- W1520290721 cites W2003992939 @default.
- W1520290721 cites W2005767645 @default.
- W1520290721 cites W2006340844 @default.
- W1520290721 cites W2006728188 @default.
- W1520290721 cites W2007888714 @default.
- W1520290721 cites W2009974737 @default.
- W1520290721 cites W2010090988 @default.
- W1520290721 cites W2011500110 @default.
- W1520290721 cites W2013607914 @default.
- W1520290721 cites W2015312906 @default.
- W1520290721 cites W2015800664 @default.
- W1520290721 cites W2015903618 @default.
- W1520290721 cites W2016137320 @default.
- W1520290721 cites W2016742756 @default.
- W1520290721 cites W2016795705 @default.
- W1520290721 cites W2017007532 @default.
- W1520290721 cites W2019864861 @default.
- W1520290721 cites W2020766314 @default.
- W1520290721 cites W2020981164 @default.
- W1520290721 cites W2021538179 @default.
- W1520290721 cites W2021758696 @default.
- W1520290721 cites W2023597898 @default.
- W1520290721 cites W2024038126 @default.
- W1520290721 cites W2029916148 @default.
- W1520290721 cites W2031375858 @default.
- W1520290721 cites W2032181734 @default.
- W1520290721 cites W2034138847 @default.
- W1520290721 cites W2034262928 @default.
- W1520290721 cites W2034826672 @default.
- W1520290721 cites W2038274162 @default.
- W1520290721 cites W2038703511 @default.
- W1520290721 cites W2040607203 @default.
- W1520290721 cites W2041288638 @default.
- W1520290721 cites W2041916290 @default.
- W1520290721 cites W2042699555 @default.
- W1520290721 cites W2043180682 @default.
- W1520290721 cites W2043856487 @default.
- W1520290721 cites W2046155059 @default.
- W1520290721 cites W2046654320 @default.
- W1520290721 cites W2046833545 @default.
- W1520290721 cites W2047199950 @default.
- W1520290721 cites W2047322527 @default.
- W1520290721 cites W2050658186 @default.
- W1520290721 cites W2051842051 @default.
- W1520290721 cites W2051904771 @default.
- W1520290721 cites W2054563740 @default.
- W1520290721 cites W2054766031 @default.
- W1520290721 cites W2056096393 @default.
- W1520290721 cites W2057160041 @default.
- W1520290721 cites W2057223673 @default.
- W1520290721 cites W2057683168 @default.