FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1520353586> ?p ?o ?g. }

• W1520353586 endingPage "436" @default.
• W1520353586 startingPage "431" @default.
• W1520353586 abstract "Conglutinin, like mannan-binding lectin (MBL) and CL-43, is a serum collectin involved in the innate immune defence system. In man, low serum MBL concentrations, resulting from mutations in the collagen region, are associated with a common opsonic defect. Plasma levels of conglutinin in cattle were assayed by rocket immunoelectrophoresis to examine whether they were genetically determined. Samples were collected from calves (309 bull-calves and 260 heifers with complex pedigree relationships). The number of respiratory infections from the 42nd to 336th day of life was recorded. The number of infections was found to be genetically determined (heritability: h2=0·31±0·07). A wide concentration range of conglutinin was found in plasma (<1·25–35 μg/ml for females, geometric mean 8·1 μg/ml, and <1·25–47 μg/ml for males, geometric mean 15·5 μg/ml), and the concentration was found to be genetically determined (heritability, h2=0·52±0·07). The analysis revealed a negative association between disease frequency and the conglutinin levels (−0·56±0·18 for female; −0·50±0·18 for male). Levels of conglutinin below the detection limit of the assay (1·25 μg/ml) were found in 2% of the animals. If these animals are assumed to be homozygous for a single recessive allele causing low concentrations a gene frequency of 0·15 could be calculated. These findings suggests that selection for resistance against infectious disease is possible in cattle and that the level of plasma conglutinin may be a helpful trait in such a breeding scheme." @default.
• W1520353586 created "2016-06-24" @default.
• W1520353586 creator A5000385602 @default.
• W1520353586 creator A5003490457 @default.
• W1520353586 creator A5029000289 @default.
• W1520353586 creator A5044402087 @default.
• W1520353586 date "1998-03-01" @default.
• W1520353586 modified "2023-10-18" @default.
• W1520353586 title "The plasma levels of conglutinin are heritable in cattle and low levels predispose to infection" @default.
• W1520353586 cites W136413030 @default.
• W1520353586 cites W1521344931 @default.
• W1520353586 cites W1544793479 @default.
• W1520353586 cites W1558269436 @default.
• W1520353586 cites W1606330082 @default.
• W1520353586 cites W1807472250 @default.
• W1520353586 cites W186237530 @default.
• W1520353586 cites W1873807548 @default.
• W1520353586 cites W1979930475 @default.
• W1520353586 cites W1987050309 @default.
• W1520353586 cites W1990986783 @default.
• W1520353586 cites W1992830524 @default.
• W1520353586 cites W2000275498 @default.
• W1520353586 cites W2011445039 @default.
• W1520353586 cites W2023559004 @default.
• W1520353586 cites W2032659614 @default.
• W1520353586 cites W2047774312 @default.
• W1520353586 cites W2054292263 @default.
• W1520353586 cites W2059303055 @default.
• W1520353586 cites W2064088579 @default.
• W1520353586 cites W2077008485 @default.
• W1520353586 cites W2100944741 @default.
• W1520353586 cites W2122947838 @default.
• W1520353586 cites W2140881670 @default.
• W1520353586 cites W2154897493 @default.
• W1520353586 cites W2173015905 @default.
• W1520353586 cites W2336701831 @default.
• W1520353586 cites W4237562276 @default.
• W1520353586 cites W4238718244 @default.
• W1520353586 cites W117826220 @default.
• W1520353586 doi "https://doi.org/10.1046/j.1365-2567.1998.00452.x" @default.
• W1520353586 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1364094" @default.
• W1520353586 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9640256" @default.
• W1520353586 hasPublicationYear "1998" @default.
• W1520353586 type Work @default.
• W1520353586 sameAs 1520353586 @default.
• W1520353586 citedByCount "35" @default.
• W1520353586 countsByYear W15203535862012 @default.
• W1520353586 countsByYear W15203535862014 @default.
• W1520353586 countsByYear W15203535862016 @default.
• W1520353586 countsByYear W15203535862018 @default.
• W1520353586 countsByYear W15203535862019 @default.
• W1520353586 countsByYear W15203535862020 @default.
• W1520353586 countsByYear W15203535862021 @default.
• W1520353586 countsByYear W15203535862023 @default.
• W1520353586 crossrefType "journal-article" @default.
• W1520353586 hasAuthorship W1520353586A5000385602 @default.
• W1520353586 hasAuthorship W1520353586A5003490457 @default.
• W1520353586 hasAuthorship W1520353586A5029000289 @default.
• W1520353586 hasAuthorship W1520353586A5044402087 @default.
• W1520353586 hasBestOaLocation W15203535862 @default.
• W1520353586 hasConcept C126322002 @default.
• W1520353586 hasConcept C133493029 @default.
• W1520353586 hasConcept C136449434 @default.
• W1520353586 hasConcept C161890455 @default.
• W1520353586 hasConcept C203014093 @default.
• W1520353586 hasConcept C54355233 @default.
• W1520353586 hasConcept C71924100 @default.
• W1520353586 hasConcept C86803240 @default.
• W1520353586 hasConcept C8891405 @default.
• W1520353586 hasConceptScore W1520353586C126322002 @default.
• W1520353586 hasConceptScore W1520353586C133493029 @default.
• W1520353586 hasConceptScore W1520353586C136449434 @default.
• W1520353586 hasConceptScore W1520353586C161890455 @default.
• W1520353586 hasConceptScore W1520353586C203014093 @default.
• W1520353586 hasConceptScore W1520353586C54355233 @default.
• W1520353586 hasConceptScore W1520353586C71924100 @default.
• W1520353586 hasConceptScore W1520353586C86803240 @default.
• W1520353586 hasConceptScore W1520353586C8891405 @default.
• W1520353586 hasIssue "3" @default.
• W1520353586 hasLocation W15203535861 @default.
• W1520353586 hasLocation W15203535862 @default.
• W1520353586 hasLocation W15203535863 @default.
• W1520353586 hasOpenAccess W1520353586 @default.
• W1520353586 hasPrimaryLocation W15203535861 @default.
• W1520353586 hasRelatedWork W1864404334 @default.
• W1520353586 hasRelatedWork W2027938917 @default.
• W1520353586 hasRelatedWork W2046464322 @default.
• W1520353586 hasRelatedWork W2102095463 @default.
• W1520353586 hasRelatedWork W2129338095 @default.
• W1520353586 hasRelatedWork W2158286998 @default.
• W1520353586 hasRelatedWork W2211496270 @default.
• W1520353586 hasRelatedWork W2220271077 @default.
• W1520353586 hasRelatedWork W2403079670 @default.
• W1520353586 hasRelatedWork W2412826784 @default.
• W1520353586 hasVolume "93" @default.
• W1520353586 isParatext "false" @default.
• W1520353586 isRetracted "false" @default.
• W1520353586 magId "1520353586" @default.

• next