Matches in SemOpenAlex for { <https://semopenalex.org/work/W1520430188> ?p ?o ?g. }
- W1520430188 endingPage "139" @default.
- W1520430188 startingPage "123" @default.
- W1520430188 abstract "Protein kinase C (PKC) isozymes catalyze the phosphorylation of substrates that play key roles in the control in proliferation, differentiation, and survival. Treatment of cells with phorbol esters, activators of classical and novel PKC isozymes, leads to a plethora of responses in a strict cell‐type–dependent specific manner. Interestingly, a few cell models undergo apoptosis in response to phorbol ester stimulation, including androgen‐dependent prostate cancer cells. This effect involves the autocrine secretion of death factors and activation of the extrinsic apoptotic cascade. We have recently found that in other models, such as lung cancer cells, phorbol esters lead to irreversible growth arrest and senescence. This chapter describes the methods we use to assess these phorbol ester responses in cancer cell models, focusing on apoptosis and senescence." @default.
- W1520430188 created "2016-06-24" @default.
- W1520430188 creator A5016162588 @default.
- W1520430188 creator A5029548499 @default.
- W1520430188 creator A5048424400 @default.
- W1520430188 creator A5068973959 @default.
- W1520430188 creator A5077192270 @default.
- W1520430188 date "2008-01-01" @default.
- W1520430188 modified "2023-09-25" @default.
- W1520430188 title "Chapter 7 Phorbol Ester–Induced Apoptosis and Senescence in Cancer Cell Models" @default.
- W1520430188 cites W1523537564 @default.
- W1520430188 cites W1554882994 @default.
- W1520430188 cites W1767727568 @default.
- W1520430188 cites W1806836340 @default.
- W1520430188 cites W1933897045 @default.
- W1520430188 cites W1964347602 @default.
- W1520430188 cites W1970857342 @default.
- W1520430188 cites W1971644781 @default.
- W1520430188 cites W1973821950 @default.
- W1520430188 cites W1975702359 @default.
- W1520430188 cites W1982952843 @default.
- W1520430188 cites W1989644689 @default.
- W1520430188 cites W1995194065 @default.
- W1520430188 cites W1995501320 @default.
- W1520430188 cites W2006668556 @default.
- W1520430188 cites W2013634259 @default.
- W1520430188 cites W2015157179 @default.
- W1520430188 cites W2018376574 @default.
- W1520430188 cites W2018816395 @default.
- W1520430188 cites W2019836798 @default.
- W1520430188 cites W2019906376 @default.
- W1520430188 cites W2020632741 @default.
- W1520430188 cites W2024209230 @default.
- W1520430188 cites W2030631466 @default.
- W1520430188 cites W2032919245 @default.
- W1520430188 cites W206098571 @default.
- W1520430188 cites W2062077798 @default.
- W1520430188 cites W2069139672 @default.
- W1520430188 cites W2087127386 @default.
- W1520430188 cites W2097672870 @default.
- W1520430188 cites W2104473825 @default.
- W1520430188 cites W2104908670 @default.
- W1520430188 cites W2106065518 @default.
- W1520430188 cites W2107411016 @default.
- W1520430188 cites W2111133130 @default.
- W1520430188 cites W2114369707 @default.
- W1520430188 cites W2114632624 @default.
- W1520430188 cites W2120966020 @default.
- W1520430188 cites W2128692119 @default.
- W1520430188 cites W2133037422 @default.
- W1520430188 cites W2133991390 @default.
- W1520430188 cites W2148760047 @default.
- W1520430188 cites W2155805035 @default.
- W1520430188 cites W2161322323 @default.
- W1520430188 cites W2163585955 @default.
- W1520430188 cites W2321945407 @default.
- W1520430188 cites W2327883130 @default.
- W1520430188 cites W2504155943 @default.
- W1520430188 doi "https://doi.org/10.1016/s0076-6879(08)01607-8" @default.
- W1520430188 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18603119" @default.
- W1520430188 hasPublicationYear "2008" @default.
- W1520430188 type Work @default.
- W1520430188 sameAs 1520430188 @default.
- W1520430188 citedByCount "22" @default.
- W1520430188 countsByYear W15204301882012 @default.
- W1520430188 countsByYear W15204301882013 @default.
- W1520430188 countsByYear W15204301882014 @default.
- W1520430188 countsByYear W15204301882015 @default.
- W1520430188 countsByYear W15204301882018 @default.
- W1520430188 countsByYear W15204301882021 @default.
- W1520430188 countsByYear W15204301882023 @default.
- W1520430188 crossrefType "book-chapter" @default.
- W1520430188 hasAuthorship W1520430188A5016162588 @default.
- W1520430188 hasAuthorship W1520430188A5029548499 @default.
- W1520430188 hasAuthorship W1520430188A5048424400 @default.
- W1520430188 hasAuthorship W1520430188A5068973959 @default.
- W1520430188 hasAuthorship W1520430188A5077192270 @default.
- W1520430188 hasConcept C11960822 @default.
- W1520430188 hasConcept C119795356 @default.
- W1520430188 hasConcept C121608353 @default.
- W1520430188 hasConcept C128240485 @default.
- W1520430188 hasConcept C1491633281 @default.
- W1520430188 hasConcept C170493617 @default.
- W1520430188 hasConcept C181199279 @default.
- W1520430188 hasConcept C185592680 @default.
- W1520430188 hasConcept C190283241 @default.
- W1520430188 hasConcept C195794163 @default.
- W1520430188 hasConcept C2780043322 @default.
- W1520430188 hasConcept C31573885 @default.
- W1520430188 hasConcept C502942594 @default.
- W1520430188 hasConcept C522857546 @default.
- W1520430188 hasConcept C54355233 @default.
- W1520430188 hasConcept C55493867 @default.
- W1520430188 hasConcept C62112901 @default.
- W1520430188 hasConcept C86803240 @default.
- W1520430188 hasConcept C95444343 @default.
- W1520430188 hasConcept C96232424 @default.
- W1520430188 hasConceptScore W1520430188C11960822 @default.