FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1520483630> ?p ?o ?g. }

• W1520483630 endingPage "2751" @default.
• W1520483630 startingPage "2741" @default.
• W1520483630 abstract "Cervical cancer screening test performance has been hampered by either lack of sensitivity of Pap cytology or lack of specificity of Human Papillomavirus (HPV) testing. This uncertainty can lead to unnecessary referral and treatment, which is disturbing for patients and increases costs for health care providers. The identification of p16 INK4a as a marker for neoplastic transformation of cervical squamous epithelial cells by HPVs allows the identification of HPV‐transformed cells in histopathology or cytopathology specimens. Diagnostic studies have demonstrated that the use of p16 INK4a immunohistochemistry substantially improves the reproducibility and diagnostic accuracy of histopathologic diagnoses. p16 INK4a cytology has substantially higher sensitivity for detection of cervical precancer in comparison to conventional Pap tests. Compared to HPV DNA tests, immunochemical detection of p16 INK4a ‐stained cells demonstrates a significantly improved specificity with remarkably good sensitivity. About 15 years after the initial observation that p16 INK4a is overexpressed in HPV‐transformed cells we review the accumulated clinical evidence suggesting that p16 INK4a can serve as a useful biomarker in the routine diagnostic work up of patients with HPV infections and associated lesions of the female anogenital tract." @default.
• W1520483630 created "2016-06-24" @default.
• W1520483630 creator A5007438121 @default.
• W1520483630 creator A5021671909 @default.
• W1520483630 creator A5024936471 @default.
• W1520483630 creator A5054984526 @default.
• W1520483630 creator A5058641567 @default.
• W1520483630 creator A5076345342 @default.
• W1520483630 creator A5089867910 @default.
• W1520483630 date "2014-05-12" @default.
• W1520483630 modified "2023-10-04" @default.
• W1520483630 title "The clinical impact of using p16^INK4a immunochemistry in cervical histopathology and cytology: An update of recent developments" @default.
• W1520483630 cites W1499170654 @default.
• W1520483630 cites W1531044908 @default.
• W1520483630 cites W1537810699 @default.
• W1520483630 cites W1668682113 @default.
• W1520483630 cites W1966481117 @default.
• W1520483630 cites W1966676297 @default.
• W1520483630 cites W1970828076 @default.
• W1520483630 cites W1970924670 @default.
• W1520483630 cites W1972279806 @default.
• W1520483630 cites W1972678560 @default.
• W1520483630 cites W1973954265 @default.
• W1520483630 cites W1974915741 @default.
• W1520483630 cites W1980750660 @default.
• W1520483630 cites W1984948591 @default.
• W1520483630 cites W1991327249 @default.
• W1520483630 cites W1993154586 @default.
• W1520483630 cites W1996113298 @default.
• W1520483630 cites W1998218812 @default.
• W1520483630 cites W1999113083 @default.
• W1520483630 cites W2000799360 @default.
• W1520483630 cites W2003194103 @default.
• W1520483630 cites W2004785738 @default.
• W1520483630 cites W2008958654 @default.
• W1520483630 cites W2009547084 @default.
• W1520483630 cites W2012016836 @default.
• W1520483630 cites W2012503416 @default.
• W1520483630 cites W2015924874 @default.
• W1520483630 cites W2021649358 @default.
• W1520483630 cites W2028750854 @default.
• W1520483630 cites W2036494363 @default.
• W1520483630 cites W2049530406 @default.
• W1520483630 cites W2052489835 @default.
• W1520483630 cites W2055082270 @default.
• W1520483630 cites W2055596206 @default.
• W1520483630 cites W2068965703 @default.
• W1520483630 cites W2071707543 @default.
• W1520483630 cites W2071848600 @default.
• W1520483630 cites W2072020531 @default.
• W1520483630 cites W2083370590 @default.
• W1520483630 cites W2088578285 @default.
• W1520483630 cites W2093587960 @default.
• W1520483630 cites W2094572867 @default.
• W1520483630 cites W2098765233 @default.
• W1520483630 cites W2100273422 @default.
• W1520483630 cites W2101341125 @default.
• W1520483630 cites W2109892705 @default.
• W1520483630 cites W2115240529 @default.
• W1520483630 cites W2116458357 @default.
• W1520483630 cites W2121732950 @default.
• W1520483630 cites W2126725601 @default.
• W1520483630 cites W2129316684 @default.
• W1520483630 cites W2134518135 @default.
• W1520483630 cites W2134564320 @default.
• W1520483630 cites W2134674929 @default.
• W1520483630 cites W2139738127 @default.
• W1520483630 cites W2140566055 @default.
• W1520483630 cites W2144175542 @default.
• W1520483630 cites W2145150089 @default.
• W1520483630 cites W2148265011 @default.
• W1520483630 cites W2149347081 @default.
• W1520483630 cites W2156793931 @default.
• W1520483630 cites W2158872827 @default.
• W1520483630 cites W2160798251 @default.
• W1520483630 cites W2164333690 @default.
• W1520483630 cites W2166467087 @default.
• W1520483630 cites W2166632132 @default.
• W1520483630 cites W2167052061 @default.
• W1520483630 cites W2281050940 @default.
• W1520483630 cites W2395982254 @default.
• W1520483630 cites W3020989840 @default.
• W1520483630 cites W93260598 @default.
• W1520483630 doi "https://doi.org/10.1002/ijc.28900" @default.
• W1520483630 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24740700" @default.
• W1520483630 hasPublicationYear "2014" @default.
• W1520483630 type Work @default.
• W1520483630 sameAs 1520483630 @default.
• W1520483630 citedByCount "80" @default.
• W1520483630 countsByYear W15204836302014 @default.
• W1520483630 countsByYear W15204836302015 @default.
• W1520483630 countsByYear W15204836302016 @default.
• W1520483630 countsByYear W15204836302017 @default.
• W1520483630 countsByYear W15204836302018 @default.
• W1520483630 countsByYear W15204836302019 @default.
• W1520483630 countsByYear W15204836302020 @default.
• W1520483630 countsByYear W15204836302021 @default.
• W1520483630 countsByYear W15204836302022 @default.

• next