FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1520551144> ?p ?o ?g. }

• W1520551144 endingPage "7" @default.
• W1520551144 startingPage "513" @default.
• W1520551144 abstract "Effects of prescribed doses of ketamine five minutes after application and influences of transesophageal echocardiography (TEE) on left ventricular, systemic arterial, and baroreflex responses were investigated to test the hypothesis that ketamine and/or TEE probe insertion alter cardiovascular function. Seven rhesus monkeys were tested under each of four randomly selected experimental conditions: (1) intravenous bolus dose of ketamine (0.5 ml), (2) continuous infusion of ketamine (500 mg/kg/min), (3) continuous infusion of ketamine (500 mg/kg/min) with TEE, and (4) control (no ketamine or TEE). Monkeys were chronically instrumented with a high fidelity, dual-sensor micromanometer to measure left ventricular and aortic pressure and a transit-time ultrasound probe to measure aortic flow. These measures were used to calculate left ventricular function. A 4-element Windkessel lumped-parameter model was used to estimate total peripheral resistance and systemic arterial compliance. Baroreflex response was calculated as the change in R-R interval divided by the change in mean aortic pressure measured during administration of graded concentrations of nitroprusside. The results indicated that five minutes after ketamine application heart rate and left ventricular diastolic compliance decreased while TEE increased aortic systolic and diastolic pressure. We conclude that ketamine may be administered as either a bolus or continuous infusion without affecting cardiovascular function 5 minutes after application while the insertion of a TEE probe will increase aortic pressure. The results for both ketamine and TEE illustrate the classic Hawthorne Effect, where the observed values are partly a function of the measurement process. Measures of aortic pressure, heart rate, and left ventricular diastolic pressure should be viewed as relative, as opposed to absolute, when organisms are sedated with ketamine or instrumented with a TEE probe." @default.
• W1520551144 created "2016-06-24" @default.
• W1520551144 creator A5004626737 @default.
• W1520551144 creator A5005813429 @default.
• W1520551144 creator A5048260827 @default.
• W1520551144 creator A5058032912 @default.
• W1520551144 creator A5058610345 @default.
• W1520551144 creator A5065758996 @default.
• W1520551144 date "2001-12-01" @default.
• W1520551144 modified "2023-09-23" @default.
• W1520551144 title "Left ventricular, systemic arterial, and baroreflex responses to ketamine and TEE in chronically instrumented monkeys." @default.
• W1520551144 cites W146121780 @default.
• W1520551144 cites W15515072 @default.
• W1520551144 cites W1823269234 @default.
• W1520551144 cites W1964623087 @default.
• W1520551144 cites W1970184705 @default.
• W1520551144 cites W1986892343 @default.
• W1520551144 cites W1991545674 @default.
• W1520551144 cites W1992000786 @default.
• W1520551144 cites W1992368692 @default.
• W1520551144 cites W1993786268 @default.
• W1520551144 cites W1996358655 @default.
• W1520551144 cites W1996879197 @default.
• W1520551144 cites W2003264542 @default.
• W1520551144 cites W2032819971 @default.
• W1520551144 cites W2039127578 @default.
• W1520551144 cites W2040015335 @default.
• W1520551144 cites W2046215109 @default.
• W1520551144 cites W2051968895 @default.
• W1520551144 cites W2057926309 @default.
• W1520551144 cites W2063305099 @default.
• W1520551144 cites W2068132840 @default.
• W1520551144 cites W2071616832 @default.
• W1520551144 cites W2091839037 @default.
• W1520551144 cites W2107625993 @default.
• W1520551144 cites W2155754546 @default.
• W1520551144 cites W2159431529 @default.
• W1520551144 cites W2407120632 @default.
• W1520551144 cites W2463005304 @default.
• W1520551144 cites W2470143444 @default.
• W1520551144 cites W85839918 @default.
• W1520551144 cites W2033567779 @default.
• W1520551144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11924813" @default.
• W1520551144 hasPublicationYear "2001" @default.
• W1520551144 type Work @default.
• W1520551144 sameAs 1520551144 @default.
• W1520551144 citedByCount "2" @default.
• W1520551144 crossrefType "journal-article" @default.
• W1520551144 hasAuthorship W1520551144A5004626737 @default.
• W1520551144 hasAuthorship W1520551144A5005813429 @default.
• W1520551144 hasAuthorship W1520551144A5048260827 @default.
• W1520551144 hasAuthorship W1520551144A5058032912 @default.
• W1520551144 hasAuthorship W1520551144A5058610345 @default.
• W1520551144 hasAuthorship W1520551144A5065758996 @default.
• W1520551144 hasConcept C126322002 @default.
• W1520551144 hasConcept C164705383 @default.
• W1520551144 hasConcept C178853913 @default.
• W1520551144 hasConcept C191237925 @default.
• W1520551144 hasConcept C26635844 @default.
• W1520551144 hasConcept C2777953023 @default.
• W1520551144 hasConcept C2780795376 @default.
• W1520551144 hasConcept C39124391 @default.
• W1520551144 hasConcept C42219234 @default.
• W1520551144 hasConcept C43376680 @default.
• W1520551144 hasConcept C71924100 @default.
• W1520551144 hasConcept C84393581 @default.
• W1520551144 hasConceptScore W1520551144C126322002 @default.
• W1520551144 hasConceptScore W1520551144C164705383 @default.
• W1520551144 hasConceptScore W1520551144C178853913 @default.
• W1520551144 hasConceptScore W1520551144C191237925 @default.
• W1520551144 hasConceptScore W1520551144C26635844 @default.
• W1520551144 hasConceptScore W1520551144C2777953023 @default.
• W1520551144 hasConceptScore W1520551144C2780795376 @default.
• W1520551144 hasConceptScore W1520551144C39124391 @default.
• W1520551144 hasConceptScore W1520551144C42219234 @default.
• W1520551144 hasConceptScore W1520551144C43376680 @default.
• W1520551144 hasConceptScore W1520551144C71924100 @default.
• W1520551144 hasConceptScore W1520551144C84393581 @default.
• W1520551144 hasIssue "6" @default.
• W1520551144 hasLocation W15205511441 @default.
• W1520551144 hasOpenAccess W1520551144 @default.
• W1520551144 hasPrimaryLocation W15205511441 @default.
• W1520551144 hasRelatedWork W1520551144 @default.
• W1520551144 hasRelatedWork W1965619193 @default.
• W1520551144 hasRelatedWork W1988343163 @default.
• W1520551144 hasRelatedWork W1999900565 @default.
• W1520551144 hasRelatedWork W2037845969 @default.
• W1520551144 hasRelatedWork W2094716164 @default.
• W1520551144 hasRelatedWork W2384242727 @default.
• W1520551144 hasRelatedWork W2397018478 @default.
• W1520551144 hasRelatedWork W2409995787 @default.
• W1520551144 hasRelatedWork W2912917448 @default.
• W1520551144 hasVolume "51" @default.
• W1520551144 isParatext "false" @default.
• W1520551144 isRetracted "false" @default.
• W1520551144 magId "1520551144" @default.
• W1520551144 workType "article" @default.