FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1520592610> ?p ?o ?g. }

• W1520592610 endingPage "11831" @default.
• W1520592610 startingPage "11826" @default.
• W1520592610 abstract "Previous studies of the human cell line RPMI-2650 (wild type) and its canavanine-resistant variants have demonstrated differences in argininosuccinate synthetase activity as follows: canavanine-resistant much greater than wild type grown in citrulline greater than wild type grown in arginine (Su, T.-S., Beaudet, A. L., and O'Brien, W. E. (1981) Biochemistry 20, 2956-2960). A recombinant plasmid containing a 1.55-kilobase insert complementary to the mRNA for human argininosuccinate synthetase was isolated by the combined use of differential colony hybridization and immunoprecipitation of the products of plasmid-selected mRNA translation. Both blot and dot hybridization analysis of polyadenylated RNA indicated a major mRNA species of 1.67 kilobase in all cells, and the levels of mRNA correlated well with the levels of enzyme activity: canavanine-resistant, 180; wild type grown in citrulline, 7; and wild type grown in arginine, 1. One major mRNA species of 1.67 kilobase and one minor species of 2.68 kilobase were observed in wild type and canavanine-resistant cell lines. Reassociation kinetics of pAS1 with genomic DNA from human liver, canavanine-resistant cells, and wild type cells were not significantly different. Blot hybridization of genomic DNA revealed no detectable differences between wild type cells, canavanine-resistant cells, and human leukocytes. The data demonstrated that there were multiple copies, perhaps 10 or more, of argininosuccinate synthetase-like sequences in human DNA and that the canavanine-resistant phenotype was not due to gene amplification." @default.
• W1520592610 created "2016-06-24" @default.
• W1520592610 creator A5015013761 @default.
• W1520592610 creator A5074963804 @default.
• W1520592610 creator A5087074480 @default.
• W1520592610 creator A5089048280 @default.
• W1520592610 date "1981-11-01" @default.
• W1520592610 modified "2023-10-13" @default.
• W1520592610 title "Cloning of cDNA for argininosuccinate synthetase mRNA and study of enzyme overproduction in a human cell line." @default.
• W1520592610 cites W1251102914 @default.
• W1520592610 cites W138180474 @default.
• W1520592610 cites W1419303435 @default.
• W1520592610 cites W1487534034 @default.
• W1520592610 cites W1507212424 @default.
• W1520592610 cites W1576307857 @default.
• W1520592610 cites W1980814484 @default.
• W1520592610 cites W1985202731 @default.
• W1520592610 cites W1988735312 @default.
• W1520592610 cites W1997554941 @default.
• W1520592610 cites W2003094013 @default.
• W1520592610 cites W2016613744 @default.
• W1520592610 cites W2019410656 @default.
• W1520592610 cites W2027411626 @default.
• W1520592610 cites W2029987769 @default.
• W1520592610 cites W2032973837 @default.
• W1520592610 cites W2044717712 @default.
• W1520592610 cites W2049586830 @default.
• W1520592610 cites W2053315689 @default.
• W1520592610 cites W2055375960 @default.
• W1520592610 cites W2062269297 @default.
• W1520592610 cites W2063450941 @default.
• W1520592610 cites W2075816835 @default.
• W1520592610 cites W2091476067 @default.
• W1520592610 cites W2123824838 @default.
• W1520592610 cites W2129931102 @default.
• W1520592610 cites W2333285502 @default.
• W1520592610 doi "https://doi.org/10.1016/s0021-9258(19)68480-2" @default.
• W1520592610 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6170638" @default.
• W1520592610 hasPublicationYear "1981" @default.
• W1520592610 type Work @default.
• W1520592610 sameAs 1520592610 @default.
• W1520592610 citedByCount "121" @default.
• W1520592610 countsByYear W15205926102014 @default.
• W1520592610 countsByYear W15205926102015 @default.
• W1520592610 countsByYear W15205926102016 @default.
• W1520592610 countsByYear W15205926102020 @default.
• W1520592610 countsByYear W15205926102021 @default.
• W1520592610 crossrefType "journal-article" @default.
• W1520592610 hasAuthorship W1520592610A5015013761 @default.
• W1520592610 hasAuthorship W1520592610A5074963804 @default.
• W1520592610 hasAuthorship W1520592610A5087074480 @default.
• W1520592610 hasAuthorship W1520592610A5089048280 @default.
• W1520592610 hasBestOaLocation W15205926101 @default.
• W1520592610 hasConcept C104317684 @default.
• W1520592610 hasConcept C105580179 @default.
• W1520592610 hasConcept C121050878 @default.
• W1520592610 hasConcept C124420848 @default.
• W1520592610 hasConcept C153911025 @default.
• W1520592610 hasConcept C164007495 @default.
• W1520592610 hasConcept C181199279 @default.
• W1520592610 hasConcept C187882448 @default.
• W1520592610 hasConcept C188610204 @default.
• W1520592610 hasConcept C199360897 @default.
• W1520592610 hasConcept C2776761436 @default.
• W1520592610 hasConcept C2777468819 @default.
• W1520592610 hasConcept C41008148 @default.
• W1520592610 hasConcept C515207424 @default.
• W1520592610 hasConcept C55493867 @default.
• W1520592610 hasConcept C86803240 @default.
• W1520592610 hasConceptScore W1520592610C104317684 @default.
• W1520592610 hasConceptScore W1520592610C105580179 @default.
• W1520592610 hasConceptScore W1520592610C121050878 @default.
• W1520592610 hasConceptScore W1520592610C124420848 @default.
• W1520592610 hasConceptScore W1520592610C153911025 @default.
• W1520592610 hasConceptScore W1520592610C164007495 @default.
• W1520592610 hasConceptScore W1520592610C181199279 @default.
• W1520592610 hasConceptScore W1520592610C187882448 @default.
• W1520592610 hasConceptScore W1520592610C188610204 @default.
• W1520592610 hasConceptScore W1520592610C199360897 @default.
• W1520592610 hasConceptScore W1520592610C2776761436 @default.
• W1520592610 hasConceptScore W1520592610C2777468819 @default.
• W1520592610 hasConceptScore W1520592610C41008148 @default.
• W1520592610 hasConceptScore W1520592610C515207424 @default.
• W1520592610 hasConceptScore W1520592610C55493867 @default.
• W1520592610 hasConceptScore W1520592610C86803240 @default.
• W1520592610 hasIssue "22" @default.
• W1520592610 hasLocation W15205926101 @default.
• W1520592610 hasOpenAccess W1520592610 @default.
• W1520592610 hasPrimaryLocation W15205926101 @default.
• W1520592610 hasRelatedWork W1833932539 @default.
• W1520592610 hasRelatedWork W1843927557 @default.
• W1520592610 hasRelatedWork W1970561666 @default.
• W1520592610 hasRelatedWork W1981867278 @default.
• W1520592610 hasRelatedWork W1992598464 @default.
• W1520592610 hasRelatedWork W1997004647 @default.
• W1520592610 hasRelatedWork W2045231956 @default.
• W1520592610 hasRelatedWork W2056190481 @default.
• W1520592610 hasRelatedWork W2091476067 @default.

• next