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• W1520786939 abstract "Longer-term mortality benefit and cost-effectiveness for abdominal aortic aneurysm (AAA) screening are uncertain.18 In addition to the mortality benefit, evidence indicating that screening is highly costeffective is increasing.2, 34 In light of this evidence, national screening programs are now being considered in many countries.47, 46 However, there is little evidence regarding long-term outcomes after AAA screening; almost all of the evidence from randomized trials is limited to the first 4 years after screening.18 It is therefore expected that cost-effectiveness of screening will improve over time.18 It is expected that the lifetime cost-effectiveness of screening will be highly favorable. Furthermore, these results show that the mortality benefit of an approximate 50% reduction in AAA-related death in patients invited to be screened is maintained at 7-year follow-up. The risk for AAA rupture remains low in patients with normal results on initial screening.18 Patients with AAA detected in selective screening at the vascular laboratory had a high level of morbidity and inferior long-term survival when compared with the general population. Elective AAA repair rate was lower in this group than in patients with AAA detected in general screening programmes, with an acceptable perioperative mortality rate. Despite these factors, selective screening for AAA among patients referred to the vascular laboratory for suspected arterial disease was cost-effective under most assumptions with an estimated ICER at base-case of 11 084 Euro/LYG compared with non-screening.28 Screening appears to reduce hospital AAA mortality and to be cost-effective.25 The benefit of inviting men aged 65-74 to screening for abdominal aortic aneurysm continues at about the same rate 7-10 years after screening, as observed in previous years. The reduction in number of deaths related to abdominal aortic aneurysm in MASS is estimated as 42% at four years34, 47% at seven years18, and now 48% at 10 years. This is surprising as it might be expected that ruptures of the aneurysm in those originally screened as normal and incidental detection of abdominal aortic aneurysm in the control group would erode the benefit over time.45" @default.
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• W1520786939 date "2011-06-22" @default.
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• W1520786939 title "Screening for Abdominal Aortic Aneurysm" @default.
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• W1520786939 doi "https://doi.org/10.5772/17846" @default.
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