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- W152099190 abstract "This chapter presents comments on the nature of receptor antibodies on T lymphocytes. There is good evidence that some T lymphocytes of immunized mice carry on their surface the public idiotype that their plasma cells are secreting in response to the antigen. A part of this evidence shows further that suppressor T cells carry these idiotypes. Another belief that may be less founded but exists is that cytotoxic T lymphocytes do not carry public idiotypes. This is based on failures to experimentally detect idiotypes CRI (8) or NP-b on T cells that are cytotoxic to haptenated syngeneic cells. Cytotoxic and helper (and DTH?) T-cells have basically different combining-site-forming polypeptides (primordial genes serving the defense against bacteria and viruses) than B cells (advanced gene loci). There is probably at least a subclass of suppressor T cells which share two characteristics with B cells. One is the origin of V regions (VH and VL genes) and the other expression of la-type structures on the cell surface." @default.
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- W152099190 date "1980-01-01" @default.
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- W152099190 title "THE NATURE OF RECEPTOR ANTIBODIES ON T LYMPHOCYTES" @default.
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- W152099190 doi "https://doi.org/10.1016/b978-0-12-637140-6.50097-8" @default.
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