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- W1521551245 abstract "Abstract: We evaluated the efficacy of loxoprofen sodium for refractory nocturia. Twelve men (mean age, 75.1 ± 5.7) with nocturia were enrolled in this study. All patients received 60 mg loxoprofen sodium prior to sleeping at night for 14 days. Nine of 12 patients (75%) felt more satisfaction than previous treatments. Patients were grouped into a loxoprofen sodium-effective (n = 7) and ineffective groups (n = 5) based on the results of the frequency-volume chart. In the effective group, interestingly, night-time urine volume showed significant reduction (P < 0.05). On the other hand, the average single voided volume at night and 24-h urine volume showed no significant change. There was a statistically significant difference in the night-time urine volume after treatment between groups (P < 0.01). Loxoprofen sodium is an effective treatment for some patients with refractory nocturia. The main effect mechanism of loxoprofen sodium may involve the reduction of night-time urine production." @default.
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- W1521551245 date "2008-04-29" @default.
- W1521551245 modified "2023-09-23" @default.
- W1521551245 title "Loxoprofen sodium treatment for elderly men with refractory nocturia: Effect on night-time urine production" @default.
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- W1521551245 doi "https://doi.org/10.1111/j.1442-2042.2008.02021.x" @default.
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