FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1521874564> ?p ?o ?g. }

• W1521874564 endingPage "9391" @default.
• W1521874564 startingPage "9384" @default.
• W1521874564 abstract "To study the antigenic conservation of epitopes of human immunodeficiency virus type 1 (HIV-1) isolates of different clades, the abilities of human anti-HIV-1 gp120 and gp41 monoclonal antibodies (MAbs) to bind to intact HIV-1 virions were determined by a newly developed virus-binding assay. Eighteen human anti-HIV MAbs, which were directed at the V2, V3 loop, CD4-binding domain (CD4bd), C5, or gp41 regions, were used. Nine HIV-1 isolates from clades A, B, D, F, G, and H were used. Microtiter wells were coated with the MAbs, after which virus was added. Bound virus was detected after lysis by testing for p24 antigen with a noncommercial p24 enzyme-linked immunosorbent assay. The anti-V3 MAbs strongly bound the four clade B viruses and viruses from the non-B clades, although binding was weaker and more sporadic with the latter. The degrees of binding by the anti-V3 MAbs to CXCR4- and CCR5-tropic viruses were similar, suggesting that the V3 loops of these two categories of viruses are similarly exposed. The anti-C5 MAbs bound isolates of clades A, B, and D. Only weak and sporadic binding of all the viruses tested with anti-CD4bd, anti-V2, and anti-gp41 MAbs was detected. These results suggest that V3 and C5 structures are shared and well exposed on intact virions of different clades compared to the CD4bd, V2, and gp41 regions." @default.
• W1521874564 created "2016-06-24" @default.
• W1521874564 creator A5005010204 @default.
• W1521874564 creator A5014347874 @default.
• W1521874564 creator A5041332295 @default.
• W1521874564 creator A5047638273 @default.
• W1521874564 creator A5049869895 @default.
• W1521874564 creator A5091016491 @default.
• W1521874564 date "1998-11-01" @default.
• W1521874564 modified "2023-10-12" @default.
• W1521874564 title "Mapping of Epitopes Exposed on Intact Human Immunodeficiency Virus Type 1 (HIV-1) Virions: a New Strategy for Studying the Immunologic Relatedness of HIV-1" @default.
• W1521874564 cites W1481233528 @default.
• W1521874564 cites W1482128944 @default.
• W1521874564 cites W1503866863 @default.
• W1521874564 cites W1512845261 @default.
• W1521874564 cites W1520182982 @default.
• W1521874564 cites W1529883997 @default.
• W1521874564 cites W1575011634 @default.
• W1521874564 cites W1576634738 @default.
• W1521874564 cites W1594767234 @default.
• W1521874564 cites W1655043483 @default.
• W1521874564 cites W1664573657 @default.
• W1521874564 cites W1860470719 @default.
• W1521874564 cites W1929811921 @default.
• W1521874564 cites W1938402363 @default.
• W1521874564 cites W1983259672 @default.
• W1521874564 cites W1990170704 @default.
• W1521874564 cites W1995407171 @default.
• W1521874564 cites W2014938502 @default.
• W1521874564 cites W2032059035 @default.
• W1521874564 cites W2032898755 @default.
• W1521874564 cites W2033928634 @default.
• W1521874564 cites W2042696055 @default.
• W1521874564 cites W2048574795 @default.
• W1521874564 cites W2060369372 @default.
• W1521874564 cites W2063561126 @default.
• W1521874564 cites W2068084279 @default.
• W1521874564 cites W2069301969 @default.
• W1521874564 cites W2069407559 @default.
• W1521874564 cites W2071516463 @default.
• W1521874564 cites W2073173214 @default.
• W1521874564 cites W2075470140 @default.
• W1521874564 cites W2088403913 @default.
• W1521874564 cites W2095632120 @default.
• W1521874564 cites W2100524711 @default.
• W1521874564 cites W2101030442 @default.
• W1521874564 cites W2106372377 @default.
• W1521874564 cites W2110917275 @default.
• W1521874564 cites W2124445678 @default.
• W1521874564 cites W2124489162 @default.
• W1521874564 cites W2128360359 @default.
• W1521874564 cites W2131906141 @default.
• W1521874564 cites W2135850892 @default.
• W1521874564 cites W2138634802 @default.
• W1521874564 cites W2147571207 @default.
• W1521874564 cites W2155920188 @default.
• W1521874564 cites W2158076986 @default.
• W1521874564 cites W2158246189 @default.
• W1521874564 cites W2159872710 @default.
• W1521874564 cites W2162071888 @default.
• W1521874564 cites W2409158291 @default.
• W1521874564 doi "https://doi.org/10.1128/jvi.72.11.9384-9391.1998" @default.
• W1521874564 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/110366" @default.
• W1521874564 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9765494" @default.
• W1521874564 hasPublicationYear "1998" @default.
• W1521874564 type Work @default.
• W1521874564 sameAs 1521874564 @default.
• W1521874564 citedByCount "106" @default.
• W1521874564 countsByYear W15218745642012 @default.
• W1521874564 countsByYear W15218745642013 @default.
• W1521874564 countsByYear W15218745642014 @default.
• W1521874564 countsByYear W15218745642015 @default.
• W1521874564 countsByYear W15218745642016 @default.
• W1521874564 countsByYear W15218745642017 @default.
• W1521874564 countsByYear W15218745642018 @default.
• W1521874564 countsByYear W15218745642019 @default.
• W1521874564 countsByYear W15218745642023 @default.
• W1521874564 crossrefType "journal-article" @default.
• W1521874564 hasAuthorship W1521874564A5005010204 @default.
• W1521874564 hasAuthorship W1521874564A5014347874 @default.
• W1521874564 hasAuthorship W1521874564A5041332295 @default.
• W1521874564 hasAuthorship W1521874564A5047638273 @default.
• W1521874564 hasAuthorship W1521874564A5049869895 @default.
• W1521874564 hasAuthorship W1521874564A5091016491 @default.
• W1521874564 hasBestOaLocation W15218745641 @default.
• W1521874564 hasConcept C104317684 @default.
• W1521874564 hasConcept C147483822 @default.
• W1521874564 hasConcept C159047783 @default.
• W1521874564 hasConcept C159654299 @default.
• W1521874564 hasConcept C195616568 @default.
• W1521874564 hasConcept C2522874641 @default.
• W1521874564 hasConcept C2776258796 @default.
• W1521874564 hasConcept C2779921545 @default.
• W1521874564 hasConcept C44465124 @default.
• W1521874564 hasConcept C542903549 @default.
• W1521874564 hasConcept C54355233 @default.
• W1521874564 hasConcept C86803240 @default.
• W1521874564 hasConcept C90132467 @default.

• next