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- W1521955119 abstract "Calcium carbonate (CaCO3)/alginate inorganic–organic hybrid particles were synthesized and deposited on to the surface of cotton fabrics with a novel one-step procedure. The effects of the Ca2+/CO32−/alginate molar ratio on the cotton matrix were investigated. The optimization of the process resulted in a regular shaped hybrid microparticles, and scanning electron microscopy revealed that the particles were uniformly distributed on the surface of the fibers. Dynamic light scattering showed that the particles were about 2 μm in diameter. Moreover, transmission electron microscopy images demonstrated that the core–shell structure of the particles existed along with CaCO3 evenly enfolded into the alginate layer. An X-ray diffraction pattern displayed that the alginate/CaCO3 hybrid microparticles were a mixture of calcite and vaterite crystal. Fourier transform infrared spectroscopy indicated that CaCO3/alginate hybrid particles formed in situ were the only deposited materials. The thermogravimetric analysis curve indicated a certain mass ratio of the alginate and CaCO3 in the hybrid particles. Furthermore, the drug-loading and drug-release properties of the hybrid microspheres were studied, and the results show that the water-soluble diclofenac sodium could be effectively loaded in the hybrid microparticles and the drug release could be effectively sustained. Finally, both of the microparticles and modified fabrics had good cytocompatibility. © 2015 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 42618." @default.
- W1521955119 created "2016-06-24" @default.
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- W1521955119 date "2015-07-07" @default.
- W1521955119 modified "2023-10-16" @default.
- W1521955119 title "Drug-loaded microparticles prepared by the one-step deposition of calcium carbonate/alginate onto cotton fabrics" @default.
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- W1521955119 doi "https://doi.org/10.1002/app.42618" @default.
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